TY - JOUR AU - da Rocha, Jaqueline Abel AU - da Silva, Natalia Chilinque Zambão AU - Silva, Ana SDN AU - Garrido, Rafael Guaresma AU - Moreira, Beatriz Meurer AU - Martins, Ianick Souto PY - 2018/09/30 Y2 - 2024/03/29 TI - Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 12 IS - 09 SE - Case Reports DO - 10.3855/jidc.10587 UR - https://jidc.org/index.php/journal/article/view/31999641 SP - 806-807 AB - <p>Non-diphtheriae <em>Corynebacterium</em> species are usually considered as contaminants of clinical specimens due to their widely environmental distribution and colonization of the human skin and mucous membranes. However, these bacteria have been increasingly recognized as agents of life-threatening infections mainly in individuals in immunosuppressive conditions. These organisms have vast variation in morphology and biochemical reaction, characteristics that make the correct identification of <em>Corynebacterium</em> at the species level extremely difficult using conventional phenotypic methods. The precise identification of <em>C. amycolatum</em> requires approaches rarely available in conventional clinical microbiology laboratories, such as API Coryne system, 16s rRNA and<em> rpoB</em> gene sequencing. In this setting, MALDI-TOF, a quick, accurate, and relatively unexpansive molecular technique, arises as a cost-effective alternative for characterizing these agents. Here, a rare and lethal case of endocarditis caused by <em>C. amycolatum</em> is presented. This is the first case of infective endocarditis due to <em>C. amycolatum</em> reported in Brazil.</p> ER -