TY - JOUR AU - Prabhurajan, Rajan AU - Kiran, Rajasekharapanicker AU - Padmavathy, Kesavaram PY - 2019/09/30 Y2 - 2024/03/29 TI - Extended Spectrum Beta-lactamase producing Salmonella Lindenberg gastroenteritis JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 13 IS - 09 SE - Case Reports DO - 10.3855/jidc.11409 UR - https://jidc.org/index.php/journal/article/view/32074097 SP - 851-853 AB - <p>Introduction: Increasing antimicrobial resistance among non-typhoidal <em>Salmonella</em> (NTS) is a major public health issue especially in developing countries and is partly due to the use of antimicrobials in animal feeds as growth promoters. NTS are often associated with self-limiting acute gastroenteritis (AGE). Nevertheless, fluoroquinolones and third-generation cephalosporins are currently used in the treatment of severe diarrhoeal infections.</p><p>Methodology: We report the case of a 30-year-old male who presented with clinical symptoms of moderate gastroenteritis. Stool culture and antibiotic susceptibility was performed as per standard microbiological methods. Molecular detection of <em>bla</em> genes was carried out by PCR.</p><p>Results: The isolate was confirmed as <em>S. Lindenberg </em>by serotyping<em>. </em>The isolate exhibited dual resistance to fluoroquinolone and third generation cephalosporins. The isolate was an ESBL producer and harboured<em> bla<sub>SHV. </sub></em>Based on the antibiotic susceptibility pattern, the patient was successfully treated with ceftriaxone-tazobactam.</p><p>Conclusion: Presently, there are no Indian reports on the <em>bla<sub>SHV</sub></em> positive ESBL producing<em> S. Lindenberg </em>gastroenteritis. We report on the successful management of the first case of acute gastroenteritis caused by <em>S. Lindenberg </em>that exhibited dual resistance to fluoroquinolone and third generation cephalosporins. Continued surveillance of the antibiotic resistance pattern of the Non-typhoidal <em>Salmonella </em>serovars circulating in the geographical region is warranted.</p> ER -