TY - JOUR AU - Bakir, Ayfer AU - Karabulut, Nuran AU - Alacam, Sema AU - Mese, Sevim AU - Somer, Ayper AU - Agacfidan, Ali PY - 2020/10/31 Y2 - 2024/03/28 TI - Investigation of human bocavirus in pediatric patients with respiratory tract infection JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 14 IS - 10 SE - Original Articles DO - 10.3855/jidc.12553 UR - https://jidc.org/index.php/journal/article/view/33175716 SP - 1191-1196 AB - <p>Introduction: Human bocavirus (HBoV) is a linear single-stranded DNA virus belonging to the <em>Parvoviridae</em> family. This study aimed to investigate the incidence of HBoV and co-infections in pediatric patients with symptoms of viral respiratory tract infection.</p><p>Methodology: This study included 2,310 patients between the ages of 0-18 in whom HBoV and other respiratory tract viral pathogens were analyzed in nasopharyngeal swab specimens.</p><p>Results: In the pediatric age group, HBoV was found in 4.5% (105/2310) of the patients and higher in children between the ages of 1 and 5. Mixed infection was detected in 43.8% (46/105) of HBoV positive patients (p = 0.10). Mono and mixed infection rates were higher in outpatients than in inpatients (p &lt; 0.05). Respiratory syncytial virus was significantly higher than the other respiratory viral pathogens (p &lt; 0.001).</p><p>Conclusions: This study is important as it is one of the rare studies performed on the incidence of HBoV in the Marmara region. In pediatric age group, the incidence of HBoV was found 4.5%. The incidence rate of HBoV in this study was similar to those in studies around the world, but close to low rates. The incidence of HBoV was found higher especially among children between the ages of 1-5 in this study. In addition to the incidence of HBoV, accompanying co-infections in the pediatric age group were also investigated in this study. Since concurrence of RSV, HRV and hMPV with HBoV was the most common it must be considered that there may be more than one agents in patients with symptoms of respiratory tract infection.</p> ER -