TY - JOUR AU - Talukder, Sudipta AU - Hasan, Md. Mehedi AU - Mandal, Amit Kumar AU - Tasmim, Syeda Tanjina AU - Parvin, Mst. Sonia AU - Ali, Md. Yamin AU - Nahar, Azimun AU - Islam, Md. Zahorul AU - Islam, Md. Taohidul PY - 2021/08/31 Y2 - 2024/03/29 TI - Epidemiology and antimicrobial resistance profiles of Salmonella in chickens, sewage, and workers of broiler farms in selected areas of Bangladesh JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 15 IS - 08 SE - Original Articles DO - 10.3855/jidc.14100 UR - https://jidc.org/index.php/journal/article/view/34516424 SP - 1155-1166 AB - <p>Introduction: A cross-sectional study was conducted to determine the prevalence and AMR pattern of <em>Salmonella</em> isolated from broiler chickens, farm sewage, and farm workers. This study also aimed at identifying the risk factors for <em>Salmonella </em>infection in chickens.</p><p>Methodology: Cloacal swabs (n = 50) from broiler chickens, farm sewage (n = 50), and hand washed water of farm workers (n = 50) were collected along with data on farm management and antimicrobial usage from 50 broiler farms of Mymensingh and Gazipur districts. All samples were analysed for the presence of <em>Salmonella</em> using selective media and PCR assay. Antimicrobial susceptibility test was done for ten antimicrobials by disk diffusion test. Risk factor analyses were carried out by multivariable logistic regression using SPSS.</p><p>Results: The overall <em>Salmonella</em> prevalence was 66% (99/150). <em>Salmonella</em> prevalence were 82% and 72% in cloacal swabs and farm sewage samples, respectively. From hand washed water, 44% of the samples were positive for <em>Salmonella</em>. <em>Salmonella </em>infection in broiler chickens was significantly associated with farming experience (≤ 5 years) and age of birds (≥ 11 days). Similar pattern of antimicrobial resistance was observed in <em>Salmonella</em> isolated from three types of samples, and high resistances were observed to colistin, doxycycline, ciprofloxacin and ceftazidime. Moreover, isolates from all the three sources showed high percentage of multidrug-resistance (80.6% to 97.6%).</p><p>Conclusions: The findings of this study reveal that antimicrobial-resistant <em>Salmonella</em> are prevailing at animal-human-environment interface, which needs an integrated approach to limit further spread of AMR.</p> ER -