TY - JOUR AU - Issack, Mohammad I AU - Neetoo, Yaseen PY - 2011/09/26 Y2 - 2024/03/29 TI - An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 5 IS - 12 SE - Outbreak DO - 10.3855/jidc.1885 UR - https://jidc.org/index.php/journal/article/view/22169781 SP - 834-839 AB - <p>Introduction:<em> Elizabethkingia meningoseptica</em> is a rare but well-recognised cause of neonatal meningitis. Reported outbreaks have involved very few cases. We describe the management and outcome of a relatively large outbreak of <em>E.meningoseptica</em> neonatal meningitis</p> <p>Methodology: From August 2002 to December 2003, eight cases of meningitis caused by <em>E. meningoseptica </em>occurred among babies admitted to the neonatal ward of Jawarhlal Nehru hospital, Mauritius. In all cases, the organism was isolated from the cerebrospinal fluid. Infection control measures were re-emphasized after each case and environmental swabs were cultured on several occasions. </p> <p>Results: The affected babies were aged 6 to 20 days (mean age of 10 days). Seven of the babies weighed < 2,500 g. All CSF isolates had the same antibiotic susceptibility pattern. Apart from one baby who died shortly after admission, all cases responded to treatment with intravenous piperacillin and oral rifampicin for three weeks. Hydrocephalus developed in two babies and was subsequently fatal in one case. At follow-up of the other cases, one baby had severe neurological sequelae but a full recovery was observed in the other four cases. The source of the outbreak could not be established conclusively. </p> <p>Conclusions: The outcome was better than what has been reported in the medical literature.   Prompt identification of the causative organism and initiation of appropriate antimicrobial therapy is essential. The combination of piperacillin and rifampicin should be considered an option for the treatment of <em>E. meningoseptica</em> neonatal meningitis if supported by properly performed antibiotic susceptibility test results. </p> ER -