TY - JOUR AU - Elaldi, Nazif AU - Gozel, Mustafa Gokhan AU - Kolayli, Fetiye AU - Engin, Aynur AU - Celik, Cem AU - Bakici, Mustafa Zahir AU - Vahaboglu, Haluk PY - 2013/05/13 Y2 - 2024/03/29 TI - Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis: a case report and literature review JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 7 IS - 05 SE - Case Reports DO - 10.3855/jidc.2820 UR - https://jidc.org/index.php/journal/article/view/23669434 SP - 424-431 AB - <p>In this report, a case of community-acquired acute bacterial meningitis (CA-ABM) caused by CTX-M-15-producing <em>Escherichia coli</em> in an elderly male patient was presented in the light of literature. Cultures of cerebrospinal fluid, blood, ear discharge, and stool samples yielded CTX-M-15-producing <em>E. coli</em> <em>in-vitro</em>, which was resistant to the extended-spectrum cephalosporins and ciprofloxacin and susceptible to imipenem, meropenem and amikacin. Meningitis was treated with parenteral meropenem plus parenteral and intraventricular amikacin administration. Since bacterial meningitis is a life-threatening infection, empiric antibiotic therapy with carbapenem can be started before the culture results are obtained, mainly in areas where the ESBL epidemiology is well known.</p> ER -