TY - JOUR AU - Boşnak, Vuslat Keçik AU - Karaoğlan, İlkay AU - Sahin, Handan Haydaroğlu AU - Namiduru, Mustafa AU - Pehlivan, Mustafa AU - Okan, Vahap AU - Mete, Ayşe Özlem PY - 2016/04/28 Y2 - 2024/03/28 TI - Evaluation of patients diagnosed with fascioliasis: A six-year experience at a university hospital in Turkey JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 10 IS - 04 SE - Original Articles DO - 10.3855/jidc.6681 UR - https://jidc.org/index.php/journal/article/view/27131001 SP - 389-394 AB - <p class="SmallText">Introduction: In this study, clinical, laboratory, radiological, and serological examinations of fascioliasis patients were analyzed, and data with a significant impact on differential diagnosis were evaluated.</p> <p class="SmallText">Methodology: Clinical, radiological, and laboratory findings and treatment responses of a total of 22 fascioliasis patients, treated between October 2009 and September 2014, were evaluated. Nineteen patients were diagnosed with fascioliasis at the invasive phase and three patients at the chronic phase. Patients were followed up for clinical, laboratory, and radiology findings for a period of three months to one year after treatment.</p> <p class="SmallText">Results: The most frequent complaints in both groups were abdominal pain, and the most common physical examination finding was epigastric tenderness. In the performed examination, an eosinophil elevation in whole blood count was detected in 19 patients (100%) in the hepatic phase, and in 2 patients (66.6%) in the biliary phase. The results of the <em>Fasciola hepatica</em> indirect hemagglutination assay (IHA) test ordered in the diagnosis were positive in all patients. Treatment with 10 mg/kg/day triclabendazole for two consecutive days was effective.</p> <p class="SmallText">Live parasites were extracted from patients in the biliary phase with endoscopic retrograde cholangiopancreatography. In the follow-ups, remission in IHA titer and clinical and radiological improvement was achieved in all patients.</p> Conclusions: If hypereosinophilia is detected by peripheral smear in patients who are admitted with complaints such as abdominal pain, weakness, nausea, myalgia, and weight loss, radiological evaluation and serological tests should be performed and fascioliasis should be considered in the differential diagnosis. ER -