TY - JOUR AU - Zambori, Csilla AU - Morvay, Attila Alexandru AU - Sala, Claudia AU - Licker, Monica AU - Gurban, Camelia AU - Tanasie, Gabriela AU - Tirziu, Emil PY - 2016/03/31 Y2 - 2024/03/29 TI - Antimicrobial effect of probiotics on bacterial species from dental plaque JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 10 IS - 03 SE - Original Articles DO - 10.3855/jidc.6800 UR - https://jidc.org/index.php/journal/article/view/27031452 SP - 214-221 AB - <p class="SmallText">Introduction: The antimicrobial role of probiotic <em>Lactobacillus casei</em> subspecies <em>casei </em>DG (<em>L. casei</em> DG) and of the mix culture of probiotic <em>Lactobacillus acidophilus </em>LA-5<em> </em>and <em>Bifidobacterium </em>BB-12<em> </em>was tested on species of <em>Staphylococcus</em>, <em>Streptococcus</em>, <em>Pasteurella</em>,<em> </em>and <em>Neisseria </em>genera from supragingival sites from dogs with dental disease of different breed, age, sex, weight, and diet. The research was conducted on these four genera because of their importance in zoonotic infections after dog bites.</p> <p class="SmallText">Methodology: Species from <em>Staphylococcus</em>, <em>Streptococcus</em>, <em>Pasteurella</em>,<em> </em>and <em>Neisseria </em>genera were isolated and identified.<em> </em>To test the antimicrobial efficacy of <em>L. casei </em>DG and the mixed culture of probiotic <em>L. acidophilus</em> LA-5 and <em>Bifidobacterium bifidum </em>BB-12 on the pathogenic species, the agar overlay method was used.</p> <p class="SmallText">Results: <em>L. casei </em>DG had a bactericidal effect on all analyzed species isolated from <em>Staphylococcus</em>, <em>Streptococcus</em>, <em>Pasteurella</em>,<em> </em>and <em>Neisseria </em>genera<em> </em>after 24 hours of incubation. The mixed probiotic culture made up of <em>L. acidophilus </em>LA-5<em> </em>and <em>Bifidobacterium </em>BB-12<em> </em>species had no bactericidal effect on the species of <em>Staphylococcus </em>and <em>Streptococcus </em>genera, which were resistant. However, it had a bacteriostatic effect on several species of <em>Pasteurella </em>and <em>Neisseria </em>genera.</p> <p class="SmallText">Conclusions: This work highlights the antimicrobial potential of probiotics <em>in vitro</em>, demonstrating that the probiotic <em>L. casei</em> DG has a bactericidal effect on all analyzed species isolated from dental plaque and that the mix culture of probiotic <em>L. acidophilus</em> LA-5 and <em>Bifidobacterium </em>BB-12 has only a bacteriostatic effect.</p> ER -