TY - JOUR AU - Qi, Xu Lin AU - Wang, Hai Xia AU - Bu, Shu Rui AU - Xu, Xiao Gang AU - Wu, Xiao Yan AU - Lin, Dong Fang PY - 2016/02/28 Y2 - 2024/03/29 TI - Incidence rates and clinical Symptoms of Salmonella, Vibrio parahaemolyticus, and Shigella infections in China, 1998–2013 JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 10 IS - 02 SE - Original Articles DO - 10.3855/jidc.6835 UR - https://jidc.org/index.php/journal/article/view/26927452 SP - 127-133 AB - <p class="SmallText">Introduction: The etiological and clinical characteristics of patients with infectious diarrhea have changed during the last decade in Shanghai.</p> <p class="SmallText">Methodology: The records of 29,210 patients with infectious diarrhea in the outpatient department of the Jinshan Hospital (Shanghai, China) between January 1998 and December 2013 were analyzed.</p> <p class="SmallText">Results: A total of 2,849 samples were positive for intestinal pathogenic bacteria including<em> Vibrio parahaemolyticus</em> (2,489; 84.0%), <em>Salmonella</em> spp. (235; 8.3%), and <em>Shigella</em> spp. (125; 4.4%). <em>V. parahaemolyticus</em> infections are mainly characterized by abdominal pain, nausea, and vomiting, whereas <em>Shigella</em> spp. infections can, in addition, induce fever. In contrast, <em>Salmonella </em>infections can produce all of these symptoms but in a smaller percentage of patients. During the 16-year study, both the number of patients and the positive infection rate declined. Notably, the rate of infections by <em>V. parahaemolyticus </em>decreased<em> </em>while the detection rates of<em> Salmonella </em>spp. increased year by year from 2006 on with the introduction of a new detection method.</p> <p class="SmallText">Conclusions: <em>Salmonella</em> has been identified as the third-most frequent cause of diarrhea from 1998–2006, as the second-most frequent cause from 2006–2010, and as the most frequent cause from 2011–2013, which was mainly due to a sharp decrease of <em>V. parahaemolyticus</em> infections in 2011–2013. <em>Salmonella </em>strains collected in 2011–2013 showed high susceptibility to imipenem (100%) and meropenem (100%), whereas susceptibilities for ampicillin (39%) and piperacillin (40%) were low.</p> ER -