TY - JOUR AU - Shabbir, Madiha AU - Aleem, Maha AU - Javed, Sundus AU - Wagner, David M AU - Keim, Paul S AU - Eqani, Syed Ali Musstjab Akbar Shah AU - Bokhari, Habib PY - 2016/08/02 Y2 - 2024/03/29 TI - Spatial analysis and identification of high risk plague regions in Pakistan based on associated rodent species distribution JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 10 IS - 07 SE - Regional Reviews DO - 10.3855/jidc.7091 UR - https://jidc.org/index.php/journal/article/view/27482799 SP - 687-693 AB - <p class="SmallText">Plague, caused by <em>Yersinia pestitis</em>, is an infectious bacterial disease that has a high fatality rate if untreated. Rodents are plague reservoirs and play an important role in disease spread. Plague cases have been reported extensively since the second pandemic from the 14th century in countries sharing borders with Pakistan, such as China and India, as well as nearby countries including Russia and central Asia. Despite being centrally located in a plague-infested geographical zone, there has been no plague incidence reported from Pakistan. This study aims to pinpoint some of the potentially important aspects of the disease, which have to be considered when assessing potential risk associated with a plague outbreak in Pakistan. In this context, the occurrence and distribution of plague-associated rodent reservoirs in different regions of Pakistan in relation to those found in the neighboring countries were mapped. In addition, the climatic factors that may also influence disease spread by affecting the growth of the bacteria are also discussed. The combined epidemiological and ecological surveillance studies suggest a prevalence of several potential rodent carriers in certain districts with the possibility of a plague outbreak in Pakistan.</p> ER -