Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique

Lucilia Lovane; Miguel J Martinez; Sergio Massora; Inacio Mandomando; Esperança Ussene; Dercio Jordao; Paola Castillo; Mamudo R Ismail; Cesaltina Lorenzoni; Carla Carrilho; Quique Bassat; Clara Menendez; Jaume Ordi; Jordi Vila; Sara Maria Soto

doi:10.3855/jidc.7306

Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique

Authors

Lucilia Lovane Maputo Central Hospital, Maputo, Mozambique
Miguel J Martinez Universitat de Barcelona, Barcelona, Spain
Sergio Massora Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique
Inacio Mandomando Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique
Esperança Ussene Maputo Central Hospital, Maputo, Mozambique
Dercio Jordao Maputo Central Hospital, Maputo, Mozambique
Paola Castillo Universitat de Barcelona, Barcelona, Spain
Mamudo R Ismail Maputo Central Hospital, Maputo, Mozambique
Cesaltina Lorenzoni Maputo Central Hospital, Maputo, Mozambique
Carla Carrilho Maputo Central Hospital, Maputo, Mozambique
Quique Bassat Universitat de Barcelona, Barcelona, Spain
Clara Menendez Universitat de Barcelona, Barcelona, Spain
Jaume Ordi Universitat de Barcelona, Barcelona, Spain
Jordi Vila Universitat de Barcelona, Barcelona, Spain
Sara Maria Soto Universitat de Barcelona, Barcelona, Spain

DOI:

https://doi.org/10.3855/jidc.7306

Keywords:

S. Typhi, carriers, corpses

Abstract

Introduction: Typhoid fever is an important public health problem in many low-income countries where asymptomatic carriers play an important role in its dissemination. The bacterium causing typhoid fever can live in the gallstones of asymptomatic persons after the infection. These carriers are reservoirs of S. Typhi, are highly contagious, and spread the disease through the secretion of bacteria in feces and urine. The aim of this study was to determine the carrier rate in an area of Mozambique.

Methodology: The presence of S. Typhi was analyzed in gallbladder samples obtained from 99 adult corpses (in-hospital deaths) from Mozambique by gold-standard culture and polymerase chain reaction (PCR).

Results: Only one sample was positive with the culture. However, nine additional samples were positive by PCR and confirmed by DNA sequencing. Thus, the prevalence of S. Typhi was 10.1% (10/99).

Conclusions: We report a high prevalence of S. Typhi in gallbladders among adult autopsy cases from Mozambique.

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Published

2016-04-28

How to Cite

Lovane L, Martinez MJ, Massora S, Mandomando I, Ussene E, Jordao D, Castillo P, Ismail MR, Lorenzoni C, Carrilho C, Bassat Q, Menendez C, Ordi J, Vila J, Soto SM (2016) Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique. J Infect Dev Ctries 10:410–412. doi: 10.3855/jidc.7306

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Issue

Vol. 10 No. 04: April 2016

Section

Brief Original Articles

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