Enteric fever in endemic areas of Indonesia: an increasing problem of resistance

Authors

  • Mochammad Hatta Department Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty Medicine, Hasanuddin University, Makassar
  • Name Ratnawati Department Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty Medicine, Hasanuddin University, Makassar

DOI:

https://doi.org/10.3855/jidc.222

Keywords:

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Abstract

Reported levels of antibiotic resistance in Salmonella Typhi from South Sulawesi, Indonesia were very low (< 1%) before 2001 and chloramphenicol remained the treatment of choice. Since 2001 however resistance has been rising and in 2007 6.8% of isolates were resistant to all three first line drugs: Ampicillin, chloramphenicol and co-trimoxazole. Ciprofloxacin resistance is currently at 3.90 %. At the same time there has been an increase in the number of reported cases. This may be because of improved diagnostics or it may be a genuine outbreak of drug resistant S. Typhi. In conclusion drug resistant typhoid fever will become a serious problem in Indonesia in the future, requiring the use of expensive drugs for the treatment of typhoid. A concerted effort is needed by the medical services to implement reliable diagnosis so that treatment or vaccination can be used to control the spread of drug resistant typhoid fever.

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Published

2008-08-01

How to Cite

1.
Hatta M, Ratnawati N (2008) Enteric fever in endemic areas of Indonesia: an increasing problem of resistance. J Infect Dev Ctries 2:279–282. doi: 10.3855/jidc.222

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