Dual infection with dengue virus 3 and human immunodeficiency virus 1 in Havana, Cuba

Authors

  • Daniel Gonzalez Department of Medicine, Pedro Kouri Tropical Medicine Institute
  • Daniel Limonta Virology Department, Pedro Kouri Tropical Medicine Institute
  • Juan Francisco Bandera Department of Medicine, Pedro Kouri Tropical Medicine Institute
  • Jorge Perez Department of Medicine, Pedro Kouri Tropical Medicine Institute
  • Gustavo Kouri Virology Department, Pedro Kouri Tropical Medicine Institute
  • Maria G. Guzman Virology Department, Pedro Kouri Tropical Medicine Institute

DOI:

https://doi.org/10.3855/jidc.131

Keywords:

dengue, HIV, coinfection, concurrent, dual, Cuba

Abstract

Although dengue virus (DEN) endemic regions overlap with human immunodeficiency virus 1 (HIV) high incidence areas, little has been documented on HIV and DEN mixed infection. Here we report DEN/HIV concurrent infections recorded during the DEN-3 epidemic in 2001-2002 in Havana. Serologic-confirmed DEN is described in two HIV-infected subjects with dengue fever symptoms. Although patients had dengue disease, the CD4+ cells remained within normal levels and no accelerated progression of HIV disease was observed. To our knowledge, DEN cases caused by DEN-3 in HIV-infected individuals have not been reported previously. Further research is needed to diagnose this likely underreported mixed viral infection in DEN endemic areas.

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Published

2009-05-01

How to Cite

1.
Gonzalez D, Limonta D, Bandera JF, Perez J, Kouri G, Guzman MG (2009) Dual infection with dengue virus 3 and human immunodeficiency virus 1 in Havana, Cuba. J Infect Dev Ctries 3:318–320. doi: 10.3855/jidc.131

Issue

Section

Case Reports