Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

Hasan M. Shihab; Fred Lutwama; Theresa Piloya; Barbara Castelnuovo; Andrew D. Kambugu; Robert Colebunders

doi:10.3855/jidc.251

Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?

Authors

Hasan M. Shihab Infectious Diseases Institute, Makerere University, Kampala
Fred Lutwama Infectious Diseases Institute, Makerere University, Kampala
Theresa Piloya Infectious Diseases Institute, Makerere University, Kampala
Barbara Castelnuovo Infectious Diseases Institute, Makerere University, Kampala
Andrew D. Kambugu Infectious Diseases Institute, Makerere University, Kampala
Robert Colebunders Infectious Diseases Institute, Makerere University, Kampala

DOI:

https://doi.org/10.3855/jidc.251

Keywords:

edema, Lopinavir/Ritonavir, resource-limited setting

Abstract

A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient attending an HIV treatment centre in Kampala, Uganda, who presented with bilateral non-tender pitting inflammatory edema two weeks after switching to a Lopinavir/Ritonavir-containing second-line treatment regimen. The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema.

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Published

2009-06-01

How to Cite

Shihab HM, Lutwama F, Piloya T, Castelnuovo B, Kambugu AD, Colebunders R (2009) Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?. J Infect Dev Ctries 3:405–407. doi: 10.3855/jidc.251

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Issue

Vol. 3 No. 05: June 2009

Section

Case Reports

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