Neonatal septicemia isolates and resistance patterns in a tertiary care hospital of North India

  • Neelam Kaistha Department of Microbiology, Government Medical College Hospital, Chandigarh
  • Manjula Mehta Department of Microbiology, Government Medical College Hospital, Chandigarh
  • Nidhi Singla Department of Microbiology, Government Medical College Hospital, Chandigarh
  • Ritu Garg Department of Microbiology, Government Medical College Hospital, Chandigarh
  • Jagdish Chander Department of Microbiology, Government Medical College Hospital, Chandigarh
Keywords: Neonates, Septicemia, Bacteriology, Antimicrobial susceptibility

Abstract

Background: Septicemia continues to be a major cause of neonatal mortality and morbidity worldwide. Methodology: To know the rate of neonatal septicemia in our tertiary care centre, a retrospective analysis of 2,247 blood samples was done over a period of four years and three months (July 2003 to October 2007). Results: During that period, a total of 296 (13.17%) blood samples were found to be positive for bacterial isolates. Gram-negative septicemia (80.40%) was identified in more cases than Gram-positive septicemia (20.60%) with Klebsiella species 84 (28.3%) being the most common isolate. Maximum resistance among Gram-negative organisms was seen in amoxycillin/ampicillin and third-generation cephalosporins. Amikacin, cefoperazone/sulbactam and imipenem were found to be good alternative drugs.  Among Gram-positive organisms, all strains were sensitive to Vancomycin.

Conclusion: Continued surveillance for various pathogens and their susceptibility profile should be done to effectively and timely treat the patients of neonatal septicaemia.

Author Biographies

Neelam Kaistha, Department of Microbiology, Government Medical College Hospital, Chandigarh

Associate Professor

Manjula Mehta, Department of Microbiology, Government Medical College Hospital, Chandigarh

Assistant Professor

Nidhi Singla, Department of Microbiology, Government Medical College Hospital, Chandigarh

Assistant Professor

Ritu Garg, Department of Microbiology, Government Medical College Hospital, Chandigarh

Demonstrator

Jagdish Chander, Department of Microbiology, Government Medical College Hospital, Chandigarh

 Professor and Head

Published
2009-11-13
How to Cite
1.
Kaistha N, Mehta M, Singla N, Garg R, Chander J (2009) Neonatal septicemia isolates and resistance patterns in a tertiary care hospital of North India. J Infect Dev Ctries 4:055-057. doi: 10.3855/jidc.625
Section
Letters to the Editor