First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt.
DOI:
https://doi.org/10.3855/jidc.386Keywords:
CTX-M ESBLs, Enterobacteriaceae, EgyptAbstract
Three pediatric isolates of Salmonella serovar Typhimurium from Egypt were reported asCTX-M-14 ESBL producers. Two of the 3 isolates (68 and 111) were 85% related by PFGE;however both were distinct from isolate 94. All three isolates produced multiple clavulanate sensitive β-lactamase bands on IEF with pIs of 7.9 and 5.4 (all isolates), while pI 8.2 enzyme was produced by isolate 94 and pI 7.4 enzyme by isolate 111. The pI 7.9 enzyme was transferable by conjugation and conferred a CTX-M ESBL phenotype. PCR and sequencing identified the CTX-M gene as CTX-M-14. Genes for OXA-1 and SHV-12 were also identified by sequencing. To our knowledge this is the first report of CTX-M-producing Salmonella in Egypt.
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Published
2009-12-14
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AbdelGhani SM, Moland ES, Black JA, Hanson ND, Goering RV, Amine MA, Saafan AE, Gaafar M, Younan M, Thomson KS (2009) First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. J Infect Dev Ctries 4:058–060. doi: 10.3855/jidc.386
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