HCV and HIV prevalences strongly correlated in Asian communities with reservoirs of HIV in high-risk groups

  • Devon D. Brewer Interdisciplinary Scientific Research
  • Adnan A. Khan Research and Development Solutions
Keywords: hepatitis C virus (HCV), human immunodeficiency virus (HIV), prevalence, iatrogenic disease

Abstract

Background: In some Asian communities, HIV epidemics initially concentrated in high-risk groups develop into generalized epidemics, while in others HIV epidemics remain confined to high-risk groups. We examined whether blood exposures in a community, as indicated by hepatitis C virus (HCV) prevalence, can account for the variability in HIV prevalence in Asia. 

Methodology: We searched the published literature for temporally comparable HCV and HIV prevalence estimates for pregnant women and other "low-risk" population segments in Asian communities with established HIV epidemics in injection drug users or prostitute women.  We assessed the correlation between HCV and HIV prevalences in these communities.

Results: HCV and HIV prevalences were strongly correlated (r = .97, p < .001). 

Conclusion: This finding suggests that blood-borne transmission drives generalized HIV epidemics in Asia and highlights the need for appropriately designed investigations of transmission modes. 

Author Biographies

Devon D. Brewer, Interdisciplinary Scientific Research

Ph.D., 1994

Adnan A. Khan, Research and Development Solutions
MBBS, MS
Published
2010-04-15
How to Cite
1.
Brewer DD, Khan AA (2010) HCV and HIV prevalences strongly correlated in Asian communities with reservoirs of HIV in high-risk groups. J Infect Dev Ctries 4:442-447. doi: 10.3855/jidc.827
Section
Original Articles