Disseminated cryptococcosis and fluconazole resistant oral candidiasis in a patient with acquired immunodeficiency syndrome (AIDS)

  • Rajendra J Kothavade Microbiology Laboratory WQA, EPCOR, Edmonton, CAnada
  • Chetan M Oberai Sir J.J. Group of Hospitals and Grant Medical College, Mumbai, India
  • Arvind G Valand Sir J.J. Group of Hospitals and Grant Medical College, Mumbai, India
  • Mehroo H Panthaki Sir H.N. Group of Hospitals and Grant Medical College, Mumbai, India
Keywords: HIV, AIDS, cryptococcosis, candidiasis, immunocompromised, fluconazole

Abstract

Disseminated cryptococcosis and recurrent oral candidiasis was presented in a-heterosexual AIDS patient. Candida tropicalis (C.tropicalis) was isolated from the oral pseudomembranous plaques and Cryptococcus neoformans (C. neoformans) was isolated from maculopapular lesions on body parts (face, hands and chest) and body fluids (urine, expectorated sputum, and cerebrospinal fluid). In vitro drug susceptibility testing on the yeast isolates demonstrated resistance to fluconazole acquired by C. tropicalis which was a suggestive possible root cause of recurrent oral candidiasis in this patient.


Author Biographies

Rajendra J Kothavade, Microbiology Laboratory WQA, EPCOR, Edmonton, CAnada
Scientist
Chetan M Oberai, Sir J.J. Group of Hospitals and Grant Medical College, Mumbai, India
Department of Dermatology, Sir JJ Group of Hospitals and Grant Medical College, Mumbai-400 008, India
Arvind G Valand, Sir J.J. Group of Hospitals and Grant Medical College, Mumbai, India
Professor and Head, Department of Pathology, Grant Medical College and Sir JJ Group of Hospitals, Mumbai-4008, India
Mehroo H Panthaki, Sir H.N. Group of Hospitals and Grant Medical College, Mumbai, India
Immunocutologist, Sir HN Hospital, Mumbai -400004, India
Published
2010-10-07
How to Cite
1.
Kothavade RJ, Oberai CM, Valand AG, Panthaki MH (2010) Disseminated cryptococcosis and fluconazole resistant oral candidiasis in a patient with acquired immunodeficiency syndrome (AIDS). J Infect Dev Ctries 4:674-678. doi: 10.3855/jidc.725
Section
Case Reports