Antibiotic screening of urine culture as a useful quality audit

  • Godwin Wilson Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, Qatar
  • Shaherudeen Badarudeen Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, Qatar
  • Angela Godwin Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar
Keywords: Urine antibiotic assay, Drug resistance, Antibiotic History, Urine culture

Abstract

Introduction: The diagnosis of urinary tract infections includes microbiologic culture of urine to determine the etiology of the infection. However, interpretation of the results can be confounded by various factors including the accuracy of a patient's history of current antibiotic usage. 

Methodology: In this report, we tested urine specimens for the presence of antibiotics and compared our results to the accuracy of antibiotic data entry on the accompanying request forms. In addition, the consequences of culturing urine specimens with incomplete antibiotic history received in the laboratory were investigated.

Results: During the study period, 14,680 urines were obtained and tested with a modified urine antibacterial substance assay (UABA). There were (97.32%) true-negative, 6 (0.04%) false-negative, 222 (1.51%) true-positive and 166 (1.13%) false-positive results. The sensitivity and specificity of this test was 97.37% and 98.85% respectively.

Conclusion: This internal audit practice demonstrates the importance of accurately completed request forms and how this information impacts the clinical interpretation of urine culture results. 

Author Biographies

Godwin Wilson, Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, Qatar
In charge Microbiology and Vice Chairman Infection Control, Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation
Shaherudeen Badarudeen, Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, Qatar
Technologist, Department of Microbiology-Al Khor, Hamad Medical Corporation.
Angela Godwin, Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar
Specialist Clinical Chemistry, Laboratory Medicine and Pathology, Hamad Medical Corporation
Published
2011-02-05
How to Cite
1.
Wilson G, Badarudeen S, Godwin A (2011) Antibiotic screening of urine culture as a useful quality audit. J Infect Dev Ctries 5:299-302. doi: 10.3855/jidc.923
Section
Brief Original Articles