A knowledge survey of obstetrics and gynecology staff on the prevention of mother-to-child transmission of hepatitis B virus

  • Yali Hu Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
  • Xinwei Dai Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
  • Yi-Hua Zhou Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
  • Huixia Yang Peking University First Hospital, Peking University, Beijing, China
Keywords: hepatitis B virus, mother-to-child transmission, immunoprophylaxis, knowledge awareness

Abstract

Introduction: This survey was designed to investigate the knowledge awareness of obstetrics and gynaecology staff (Obs/Gyn staff) on the prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV).

Methodology: Obs/Gyn staff from 21 of the 31 Chinese mainland provinces, who attended medical meetings or training classes from July to October 2011, were invited to complete a questionnaire regarding PMTCT of HBV. The questionnaire included the clinical implications of HBV serologic markers and PMTCT preventive measures for both pregnant women and infants.

Results: A total of 828 questionnaires were distributed, 617 (74.5%) Obs/Gyn staff participated in the survey, and 559 (90.6%) questionnaires met the inclusion criteria. Overall, 90% of participants correctly determined the positive hepatitis B surface antigen (HBsAg) as infectious, but up to 27.5% mistakenly considered the presence of anti-HBe and/or anti-HBc with negative HBsAg as infectious. In total, 96.3% respondents knew that pregnant women should be screened for HBV infection, and 95.3% realized that infants of HBsAg-positive mothers should be injected with hepatitis B immunoglobulin and vaccine. On the other hand, with the available immunoprophylaxis, 13.8% participants mistakenly believed caesarean section may prevent HBV mother-to-child transmission, and only 13% correctly answered that newborns of HBsAg positive mothers may be breastfed.

Conclusion: Obs/Gyn staff in China have mastered the strategies of HBV PMTCT, but there is obvious insufficiency in details of the application. Intensified efforts to train the Obs/Gyn staff are required to improve the current suboptimal medical service in HBV-exposed infants and to control mother-to-infant transmission of HBV.

Author Biographies

Yali Hu, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
Professor of Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University
Yi-Hua Zhou, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
Professor of Departments of Experimental Medicine and Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School
Huixia Yang, Peking University First Hospital, Peking University, Beijing, China

Professor of Department of Obstetrics and Gynecology, Peking University First Hospital, Peking University

Published
2013-05-13
How to Cite
1.
Hu Y, Dai X, Zhou Y-H, Yang H (2013) A knowledge survey of obstetrics and gynecology staff on the prevention of mother-to-child transmission of hepatitis B virus. J Infect Dev Ctries 7:391-397. doi: 10.3855/jidc.2915
Section
Original Articles