Sweet’s syndrome: a very rare association with pulmonary tuberculosis

  • Partha Sarathi Karmakar North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Pasang Lahmu Sherpa North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Achintya Narayan Ray North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Bikram Kr. Saha North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Tuhin Santra North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Sanchita Saha North Bengal Medical College and Hospital, Siliguri, West Bengal, India
  • Indranil Chakrabarti North Bengal Medical College and Hospital, Siliguri, West Bengal, India

Abstract

Mycobacterium tuberculosis infection is a common infection in developing countries, including India. It can induce several cutaneous reactions such as erythema nodosum, and erythema induratum; however, association of tuberculosis with Sweet’s syndrome (also known as acute febrile neutrophilic dermatosis) is extremely rare. Here we present an interesting case of sputum-positive pulmonary tuberculosis with Sweet’s syndrome. A 55-year-old female who was receiving a regimen of four antitubercular drugs (isoniazid, rifampicin, pyrazinamide, ethambutol- HRZE) for six weeks for sputum-positive pulmonary tuberculosis developed new onset high-grade fever for 15 days along with multiple reddish brown plaques and nodules involving the face as well as all four limbs of the body. Histopathology of the skin lesion was suggestive of Sweet’s syndrome. The patient responded well to immunosuppressive steroid therapy.

Author Biographies

Partha Sarathi Karmakar, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Associate Professor, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Pasang Lahmu Sherpa, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Assistant Professor, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Achintya Narayan Ray, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Assistant Professor, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Bikram Kr. Saha, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Assistant Professor, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Tuhin Santra, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Post Graduate Trainee, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Sanchita Saha, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Post Graduate Trainee, Department of Medicine, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Indranil Chakrabarti, North Bengal Medical College and Hospital, Siliguri, West Bengal, India
Assistant Professor, Department of Pathology, North Bengal Medical College & Hospital, Siliguri, West Bengal.
Published
2013-05-13
How to Cite
Karmakar P, Sherpa P, Ray A, Saha B, Santra T, Saha S, Chakrabarti I (2013) Sweet’s syndrome: a very rare association with pulmonary tuberculosis. The Journal Of Infection In Developing Countries 7 (05): 417-420. https://doi.org/10.3855/jidc.2606
Section
Case Reports

Keywords

acute febrile neutrophilic dermatosis; erythema nodosum; pyoderma gangrenosum