Antibiotic resistance and detection of the sul2 gene in urinary isolates of Escherichia coli in patients from Brazil

  • Aline Teichmann Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
  • Homero Neto de Cunha Agra Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
  • Luciana de Souza Nunes Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
  • Marion Pereira da Rocha Laboratory Enzilab, Santa Cruz do Sul, Brazil
  • Jane Dagmar Pollo Renner Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
  • Lia Gonçalves Possuelo Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
  • Marcelo Carneiro Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
  • Alexandre Rieger Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
  • Lisianne Brittes Benitez Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
  • Andréia Rosane de Moura Valim Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Keywords: urinary tract infection, antibiotic agents, resistance

Abstract

Introduction: The present study aimed to assess the antibiotic resistance profiles and detect the presence of the sul2 gene in sulfamethoxazole-susceptible and resistant isolates of Escherichia coli obtained from outpatients and inpatients with urinary tract infections.

Methodology: The resistance profiles of 739 strains were assessed and the presence of the sul2 gene in 100 isolates was tested.

Results: The antibiotics with the highest resistance rates were ampicillin (57.4%) and trimethoprim-sulfamethoxazole (44.7%). The presence of the gene sul2 was detected in 66.7% of outpatient samples and 67.9% of inpatient samples.

Conclusions: Our results demonstrate that E. coli isolates exhibit high resistance to various classes of antibiotics, highlighting the need for developing strategies to help in prescribing antibiotics.

Author Biographies

Aline Teichmann, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Doctoral Student at the Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Homero Neto de Cunha Agra, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil

Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.

Luciana de Souza Nunes, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Doctoral Student at the Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Marion Pereira da Rocha, Laboratory Enzilab, Santa Cruz do Sul, Brazil

Biochemist at the Laboratory Enzilab, Santa Cruz do Sul, Brazil.

Jane Dagmar Pollo Renner, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Lia Gonçalves Possuelo, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Marcelo Carneiro, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Alexandre Rieger, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Lisianne Brittes Benitez, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Andréia Rosane de Moura Valim, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil
Professor at the Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Published
2014-01-15
How to Cite
1.
Teichmann A, Agra HN de C, Nunes L de S, Rocha MP da, Renner JDP, Possuelo LG, Carneiro M, Rieger A, Benitez LB, Valim AR de M (2014) Antibiotic resistance and detection of the sul2 gene in urinary isolates of Escherichia coli in patients from Brazil. J Infect Dev Ctries 8:039-043. doi: 10.3855/jidc.3380
Section
Original Articles