Prevalence of "anti-HBc alone" among Syrian blood donors
DOI:
https://doi.org/10.3855/jidc.3827Keywords:
anti-HBc, anti-HBc alone, occult HBV infection, blood donors, SyriaAbstract
Introduction: We aimed to evaluate the prevalence of "anti-HBc alone" among Syrian blood donors, highlighting the possibility of representing occult HBV infection.
Methodology: Sera of 3,896 healthy blood donors were tested for both HBsAg and anti-HBc. HBsAg-negative, anti-HBc-positive samples were further tested for the antibodies to HBsAg (anti-HBs), and "anti-HBc alone" sera were tested for HBV DNA.
Results: Of 3,830 HBsAg-negative donors, 63 were "anti-HBc alone" donors, five of whom were HBV DNA positive.
Conclusions: Greater consideration should be given to the "anti-HBc alone" serological profile in blood screening, premarital testing, organ transplantation tests, and other HBV transmission-related procedures in Syria.
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