Prevalence of "anti-HBc alone" among Syrian blood donors

  • Wael Muselmani Faculty of Pharmacy, Damascus University, Damascus, Syria.
  • Wafa Habbal AL-Assad Hospital, Damascus University, P.O. Box 10769, Damascus, Syria
  • Fawza Monem Faculty of Pharmacy, Damascus University, Damascus, Syria.
Keywords: anti-HBc, anti-HBc alone, occult HBV infection, blood donors, Syria

Abstract

Introduction: We aimed to evaluate the prevalence of "anti-HBc alone" among Syrian blood donors, highlighting the possibility of representing occult HBV infection.

Methodology: Sera of 3,896 healthy blood donors were tested for both HBsAg and anti-HBc. HBsAg-negative, anti-HBc-positive samples were further tested for the antibodies to HBsAg (anti-HBs), and "anti-HBc alone" sera were tested for HBV DNA.

Results: Of 3,830 HBsAg-negative donors, 63 were "anti-HBc alone" donors, five of whom were HBV DNA positive.

Conclusions: Greater consideration should be given to the "anti-HBc alone" serological profile in blood screening, premarital testing, organ transplantation tests, and other HBV transmission-related procedures in Syria.

Published
2014-08-13
How to Cite
1.
Muselmani W, Habbal W, Monem F (2014) Prevalence of "anti-HBc alone" among Syrian blood donors. J Infect Dev Ctries 8:1013-1015. doi: 10.3855/jidc.3827
Section
Original Articles