One year experience using mycobacterial blood cultures to diagnose tuberculosis in patients with prolonged fever in Vietnam

  • Diep NT Nguyen Wellcome Trust Major Overseas Program Vietnam, Oxford University Clinical Research Unit (OUCRU), Hanoi, Vietnam
  • Trung V Nguyen National Hospital for Tropical Diseases (NHTD), Hanoi, Vietnam
  • Trinh T Dao National Hospital for Tropical Diseases (NHTD), Hanoi, Vietnam
  • Lam T Nguyen National Hospital for Tropical Diseases (NHTD), Hanoi, Vietnam
  • Peter Horby Wellcome Trust Major Overseas Program Vietnam, Oxford University Clinical Research Unit (OUCRU), Hanoi, Vietnam
  • Kinh Van Nguyen National Hospital for Tropical Diseases (NHTD), Hanoi, Vietnam
  • Heiman FL Wertheim Wellcome Trust Major Overseas Program Vietnam, Oxford University Clinical Research Unit (OUCRU), Hanoi, Vietnam
Keywords: tuberculosis, blood culture, HIV

Abstract

Introduction: To evaluate the use of mycobacterial blood cultures (MBC) in diagnosing tuberculosis (TB) in patients with prolonged fever admitted to a Vietnamese referral hospital.

Results: MBCs from 94 patients (66% male; median age 33 years; 75% HIV positive) were evaluated: 14 were mycobacterium positive (all HIV positive), and MBC was the only positive specimen in 9 cases (41%). Three positive cases were identified as Mycobacterium avium and the remaining M. tuberculosis (one case could not be identified).

Conclusion: MBC can be a valuable additional method to diagnose TB, particularly in immunosuppressed HIV patients when sputum cannot be collected.

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Author Biography

Heiman FL Wertheim, Wellcome Trust Major Overseas Program Vietnam, Oxford University Clinical Research Unit (OUCRU), Hanoi, Vietnam
OUCRU Hanoo
Published
2014-12-15
How to Cite
1.
Nguyen DN, Nguyen TV, Dao TT, Nguyen LT, Horby P, Nguyen KV, Wertheim HF (2014) One year experience using mycobacterial blood cultures to diagnose tuberculosis in patients with prolonged fever in Vietnam. J Infect Dev Ctries 8:1620-1624. doi: 10.3855/jidc.4895
Section
Brief Original Articles