Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria

Maysa Mahfoud; Mona Al Najjar; Abdul Rezzak Hamzeh

doi:10.3855/jidc.5643

Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria

Authors

Maysa Mahfoud Faculty of Pharmacy, University of Aleppo, Aleppo, Syria
Mona Al Najjar Centralized Clinical Microbiological Laboratory in Albasel and Ibn Rushd Hospitals, Aleppo, Syria
Abdul Rezzak Hamzeh Department of Biochemistry and Microbiology, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria

DOI:

https://doi.org/10.3855/jidc.5643

Keywords:

Pseudomonas aeruginosa, nosocomial infections, multidrug resistance, respiratory infections, urinary infections, Syria

Abstract

Introduction: Pseudomonas aeruginosa represents a serious clinical challenge due to its frequent involvement in nosocomial infections and its tendency towards multidrug resistance.

Methodology: This study uncovered antibiotic susceptibility patterns in 177 isolates from inpatients in three key hospitals in Aleppo, the largest city in Syria.

Results: Exceptionally low susceptibility to most routinely used antibiotics was uncovered; resistance to ciprofloxacin and gentamicin was 64.9% and 70.3%, respectively. Contrarily, susceptibility to colistin was the highest (89.1%).

Conclusions: Multidrug resistance was rife, found at a rate of 53.67% among studied P. aeruginosa isolates.

Author Biography

Abdul Rezzak Hamzeh, Department of Biochemistry and Microbiology, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria

Abdul Rezzak Hamzeh is a tenure-track assistant professor in molecular biology at the university of Aleppo. He received his PhD in molecular biology and genetics from the university of Manchester, UK. His publications include: “Prevalence of antibiotic resistance among Acinetobacter baumannii isolates from Aleppo, Syria” Am J Infect Control 2012 and “Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer Risk: A case–control study in Syria” Breast Cancer 2011.

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Published

2015-02-19

How to Cite

Mahfoud M, Al Najjar M, Hamzeh AR (2015) Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria. J Infect Dev Ctries 9:210–213. doi: 10.3855/jidc.5643

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Issue

Vol. 9 No. 02: February 2015

Section

Brief Original Articles

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