Clinical variables associated with disability in leprosy cases in northeast Brazil

  • Victor Santana Santos Postgraduate Program in Health Sciences, Federal University of Sergipe, Brazil
  • Andressa Mayara Santos de Matos Federal University of Sergipe, Brazil
  • Lorena Sheila Alves de Oliveira Federal University of Sergipe, Brazil
  • Ligia Mara Dolce de Lemos Federal University of Sergipe, Brazil
  • Ricardo Queiroz Gurgel Federal University of Sergipe, Brazil
  • Francisco Prado Reis University of Tiradentes, Brazil
  • Vanessa Tavares de Gois Santos Federal University of Sergipe, Brazil
  • Vera Lúcia Corrêa Feitosa Federal University of Sergipe, Brazil
Keywords: leprosy, physical disability, epidemiology

Abstract

Introduction: The clinical outcomes of leprosy include complications such as physical disabilities and deformities that vary according to the degree of impairment of nerve trunks. Knowledge of the factors that lead to the development of these complications is important for disability prevention programs. This study aimed to evaluate clinical factors associated with the occurrence of physical disability in leprosy cases.

Methodology: This was a retrospective study of 2,358 cases of leprosy in Aracaju, northeast Brazil, between 2001 and 2011. Analysis was done using the Chi-square test and logistic regression model.

Results: Significant factors associated with disability were found to be male gender, having more than two affected nerves, multibacillary leprosy classification, leprosy reaction, and lepromatous leprosy. The multivariate analysis revealed that the associated factors included having more than two affected nerves, leprosy reaction (adjusted odds ratio [aOR]: 2.02, 95% confidence interval [CI]: 1.36 to 3.01), the multibacillary form (aOR: 2.74, 95% CI: 1.84 to 4.08), and lepromatous leprosy (aOR: 4.87, 95% CI: 2.86 to 16.08).

Conclusions: The number of affected nerves, leprosy reaction, operational classification, and clinical presentation were identified as the main factors associated with the development of disability in leprosy patients.

Author Biographies

Victor Santana Santos, Postgraduate Program in Health Sciences, Federal University of Sergipe, Brazil

Postgraduate Program in Health Sciences, Federal University of Sergipe, Brazil.

Department of Nursing, Federal University of Sergipe, Brazil

Andressa Mayara Santos de Matos, Federal University of Sergipe, Brazil
Department of Nursing, Federal University of Sergipe, Brazil
Lorena Sheila Alves de Oliveira, Federal University of Sergipe, Brazil
Department of Nursing, Federal University of Sergipe, Brazil
Ligia Mara Dolce de Lemos, Federal University of Sergipe, Brazil
Department of Nursing, Federal University of Sergipe, Brazil
Ricardo Queiroz Gurgel, Federal University of Sergipe, Brazil
Postgraduate Program in Health Sciences, Federal University of Sergipe, Brazil
Francisco Prado Reis, University of Tiradentes, Brazil
Technological Research Institute, University of Tiradentes, Brazil
Vanessa Tavares de Gois Santos, Federal University of Sergipe, Brazil
Department of Dentistry, Federal University of Sergipe, Brazil
Vera Lúcia Corrêa Feitosa, Federal University of Sergipe, Brazil
Department of Morphology, Federal University of Sergipe, Brazil
Published
2015-03-02
How to Cite
1.
Santos VS, Santos de Matos AM, Alves de Oliveira LS, Dolce de Lemos LM, Gurgel RQ, Reis FP, Tavares de Gois Santos V, Feitosa VLC (2015) Clinical variables associated with disability in leprosy cases in northeast Brazil. J Infect Dev Ctries 9:232-238. doi: 10.3855/jidc.5341
Section
Original Articles