Global impact of Torque teno virus infection in wild and domesticated animals

  • Aldo Manzin Clinical Microbiology and Virology Unit, University of Cagliari, Cagliari, Italy
  • Francesca Mallus Clinical Microbiology and Virology Unit, University of Cagliari, Cagliari, Italy
  • Lisa Macera Clinical Microbiology and Virology Unit, University of Cagliari, Cagliari, Italy
  • Fabrizio Maggi Virology Unit, Pisa University Hospital, Pisa, Italy
  • Sylvain Blois Clinical Microbiology and Virology Unit, University of Cagliari, Cagliari, Italy
Keywords: TT virus, anellovirus, animals, ssDNA, epidemiology

Abstract

Infection with Torque teno viruses (TTVs) is not restricted to humans. Different domestic and wild animal species are naturally infected with species-specific TTVs worldwide. Due to the global spread of the infection, it is likely that essentially all animals are naturally infected with species-specific TTVs, and that co-evolution of TTVs with their hosts probably occurred. Although TTVs are potentially related to many diseases, the evidence of the widespread infection in healthy human and nonhuman hosts raised doubts about their pathogenic potential. Nonetheless, their role as superimposed agents of other diseases or as triggers for impairment of immune surveillance is currently under debate. The possible contribution of animal TT viruses to interspecies transmission and their role as zoonotic agents are currently topics of discussion.

Published
2015-07-04
How to Cite
1.
Manzin A, Mallus F, Macera L, Maggi F, Blois S (2015) Global impact of Torque teno virus infection in wild and domesticated animals. J Infect Dev Ctries 9:562-570. doi: 10.3855/jidc.6912
Section
Reviews