Lactococcus lactis spp lactis infection in infants with chronic diarrhea: two cases report and literature review in children

  • Ayse Karaaslan School of Medicine, Marmara University, Istanbul, Turkey
  • Ahmet Soysal School of Medicine, Marmara University, Istanbul, Turkey
  • EDA Kepenekli Kadayifci School of Medicine, Marmara University, Istanbul, Turkey
  • Nurhayat Yakut School of Medicine, Marmara University, Istanbul, Turkey
  • Sevliya Ocal Demir School of Medicine, Marmara University, Istanbul, Turkey
  • Gulsen Akkoc School of Medicine, Marmara University, Istanbul, Turkey
  • Serkan Atici School of Medicine, Marmara University, Istanbul, Turkey
  • Abdurrahman Sarmis School of Medicine, Marmara University, Istanbul, Turkey
  • Nurver Ulger Toprak School of Medicine, Marmara University, Istanbul, Turkey
  • Mustafa Bakir School of Medicine, Marmara University, Istanbul, Turkey
Keywords: Lactococcus lactis, infant, infection, gastrointestinal surgery

Abstract

Lactococcus lactis is a gram-positive, facultative anaerobic coccus that is occasionally isolated from human mucocutaneous surfaces such as the intestines. It is used in the dairy industry for milk acidification and is mostly nonpathogenic in immunocompetent humans, however a number of cases of infection with L. lactis have been reported in recent years. In this article, we describe two cases of infection due to L. lactis in patients with chronic diarrhea. The first case is a five-month-old boy who was operated on for volvulus on his first day of life and had ileostomy with subsequent diagnosis of chronic diarrhea and bacteremia due to L. Lactis. The second case is a six-month-old girl with the diagnosis of chronic diarrhea that developed after a catheter-related bloodstream infection. Both of the infections due to L. Lactis spp lactis were successfully treated with intravenous vancomycin therapy. Although Lactococcus species is mostly known as nonpathogenic, it should be kept in mind as a potential pathogen, especially in patients with gastrointestinal disorders.

Author Biographies

Ayse Karaaslan, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Ahmet Soysal, School of Medicine, Marmara University, Istanbul, Turkey
Professor, Department of Pediatrics and Division of Pediatric Infectious Diseases (Corresponding Author)
EDA Kepenekli Kadayifci, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Nurhayat Yakut, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Sevliya Ocal Demir, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Gulsen Akkoc, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Serkan Atici, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Pediatrics and Division of Pediatric Infectious Diseases
Abdurrahman Sarmis, School of Medicine, Marmara University, Istanbul, Turkey
Dr, Department of Microbiology
Nurver Ulger Toprak, School of Medicine, Marmara University, Istanbul, Turkey
Professor, Department of Microbiology
Mustafa Bakir, School of Medicine, Marmara University, Istanbul, Turkey
Professor, Department of Pediatrics and Division of Pediatric Infectious Diseases
Published
2016-03-31
How to Cite
1.
Karaaslan A, Soysal A, Kepenekli Kadayifci E, Yakut N, Ocal Demir S, Akkoc G, Atici S, Sarmis A, Ulger Toprak N, Bakir M (2016) Lactococcus lactis spp lactis infection in infants with chronic diarrhea: two cases report and literature review in children. J Infect Dev Ctries 10:304-307. doi: 10.3855/jidc.7049
Section
Case Reports