Characterization of Staphylococcus aureus from Human Immunodeficiency Virus (HIV) patients in Accra, Ghana

Authors

  • Beverly Egyir Statens Serum Institut, Copenhagen, Denmark
  • Akwasi Ampofo Oteng School of Allied Health, Accra, Ghana
  • Enid Owusu School of Allied Health, Accra-Ghana
  • Mercy Jemimah Newman University of Ghana Medical School, Accra, Ghana
  • Kennedy Kwasi Addo Noguchi Memorial Institute for Medical Research, Accra, Ghana
  • Anders Rhod-Larsen Statens Serum Institut, Copenhagen, Denmark

DOI:

https://doi.org/10.3855/jidc.7428

Keywords:

Staphylococcus aureus, nasal carriage, HIV patients, Africa

Abstract

Introduction: The aims of this study were to: a) determine the nasal carriage prevalence of Stahpylococcus aureus among HIV patients, b) to characterize S. aureus strains isolated.

Methodology: Characterization of S. aureus isolates was done by antibiotyping, spa typing, and detection of Panton-Valentine leukocidin (PVL) genes.

Results: S. aureus isolated (10/124; 8%)  belonged to spa types t084 (n = 3), t10828 (n = 2), t311, t304, t774, t645, and t091. The isolates were resistant to penicillin (100%), tetracycline (40%), rifampicin (10%), fucidic acid (10%), norfloxacin (10%), erythromycin (10%), and sulfamethoxazole trimethoprim (10%). Multidrug resistance (MDR) was detected in 30% of the isolates.

Conclusion: The finding of MDR S. aureus among HIV-positive patients suggests that surveillance of antimicrobial resistant S. aureus among this patient group could be considered as an infection control measure in the hospital.

Author Biographies

Beverly Egyir, Statens Serum Institut, Copenhagen, Denmark

Beverly Egyir (PhD)

Medical Research Scientist

Bacteriology Department, NMIMR

Akwasi Ampofo Oteng, School of Allied Health, Accra, Ghana

Akwasi Ampofo Oteng (Student)

Department of Medical Laboratory Sciences, School of Allied Health, Accra-Ghana

Enid Owusu, School of Allied Health, Accra-Ghana

Enid Owusu (PhD)

Lecturer

Department of Medical Laboratory Sciences, School of Allied Health, Accra-Ghana

Mercy Jemimah Newman, University of Ghana Medical School, Accra, Ghana

Mercy Jemimah Newman (Professor)

Department of Microbiology, University of Ghana Medical School, Accra, Ghana

 

Kennedy Kwasi Addo, Noguchi Memorial Institute for Medical Research, Accra, Ghana

Kwasi Kennedy Addo (Professor)

Department of Bacteriology Noguchi Memorial Institute for Medical Research, Accra, Ghana

 

Anders Rhod-Larsen, Statens Serum Institut, Copenhagen, Denmark

Anders Rhod Larsen, PhD

Head, Staphylococcus aureus department

Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

Downloads

Published

2016-05-31

How to Cite

1.
Egyir B, Oteng AA, Owusu E, Newman MJ, Addo KK, Rhod-Larsen A (2016) Characterization of Staphylococcus aureus from Human Immunodeficiency Virus (HIV) patients in Accra, Ghana. J Infect Dev Ctries 10:453–456. doi: 10.3855/jidc.7428

Issue

Vol. 10 No. 05: May 2016

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
Crossref
Scopus
Google Scholar
Europe PMC