Characterization of Staphylococcus aureus from Human Immunodeficiency Virus (HIV) patients in Accra, Ghana

  • Beverly Egyir Statens Serum Institut, Copenhagen, Denmark
  • Akwasi Ampofo Oteng School of Allied Health, Accra, Ghana
  • Enid Owusu School of Allied Health, Accra-Ghana
  • Mercy Jemimah Newman University of Ghana Medical School, Accra, Ghana
  • Kennedy Kwasi Addo Noguchi Memorial Institute for Medical Research, Accra, Ghana
  • Anders Rhod-Larsen Statens Serum Institut, Copenhagen, Denmark
Keywords: Staphylococcus aureus, nasal carriage, HIV patients, Africa

Abstract

Introduction: The aims of this study were to: a) determine the nasal carriage prevalence of Stahpylococcus aureus among HIV patients, b) to characterize S. aureus strains isolated.

Methodology: Characterization of S. aureus isolates was done by antibiotyping, spa typing, and detection of Panton-Valentine leukocidin (PVL) genes.

Results: S. aureus isolated (10/124; 8%)  belonged to spa types t084 (n = 3), t10828 (n = 2), t311, t304, t774, t645, and t091. The isolates were resistant to penicillin (100%), tetracycline (40%), rifampicin (10%), fucidic acid (10%), norfloxacin (10%), erythromycin (10%), and sulfamethoxazole trimethoprim (10%). Multidrug resistance (MDR) was detected in 30% of the isolates.

Conclusion: The finding of MDR S. aureus among HIV-positive patients suggests that surveillance of antimicrobial resistant S. aureus among this patient group could be considered as an infection control measure in the hospital.

Author Biographies

Beverly Egyir, Statens Serum Institut, Copenhagen, Denmark

Beverly Egyir (PhD)

Medical Research Scientist

Bacteriology Department, NMIMR

Akwasi Ampofo Oteng, School of Allied Health, Accra, Ghana

Akwasi Ampofo Oteng (Student)

Department of Medical Laboratory Sciences, School of Allied Health, Accra-Ghana

Enid Owusu, School of Allied Health, Accra-Ghana

Enid Owusu (PhD)

Lecturer

Department of Medical Laboratory Sciences, School of Allied Health, Accra-Ghana

Mercy Jemimah Newman, University of Ghana Medical School, Accra, Ghana

Mercy Jemimah Newman (Professor)

Department of Microbiology, University of Ghana Medical School, Accra, Ghana

 

Kennedy Kwasi Addo, Noguchi Memorial Institute for Medical Research, Accra, Ghana

Kwasi Kennedy Addo (Professor)

Department of Bacteriology Noguchi Memorial Institute for Medical Research, Accra, Ghana

 

Anders Rhod-Larsen, Statens Serum Institut, Copenhagen, Denmark

Anders Rhod Larsen, PhD

Head, Staphylococcus aureus department

Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

Published
2016-05-31
How to Cite
1.
Egyir B, Oteng AA, Owusu E, Newman MJ, Addo KK, Rhod-Larsen A (2016) Characterization of Staphylococcus aureus from Human Immunodeficiency Virus (HIV) patients in Accra, Ghana. J Infect Dev Ctries 10:453-456. doi: 10.3855/jidc.7428
Section
Original Articles