Causes of visual impairment in patients with ocular toxoplasmosis

  • Nedime Şahinoğlu Keşkek Adana Numune Training and Research Hospital, Adana, Turkey
  • Fikret Ünal Adana Numune Training and Research Hospital, Adana, Turkey
  • Selim Cevher Adana Numune Training and Research Hospital, Adana, Turkey
  • Şakir Özgür Keşkek Adana Numune Training and Research Hospital, Adana, Turkey
Keywords: Chorioretinitis, macula, ocular toxoplasmosis, optical coherence tomography, vitritis

Abstract

Introduction: The aim of this study was to report the causes of visual impairment in patients with the classic clinical presentation of ocular toxoplasmosis (OT).

Methodology: Eight patients with OT underwent standardized ophthalmologic examination and fundus imaging. Macula and the lesions that could be visualized were evaluated by spectral domain optical coherence tomography (SOCT) at presentation. The scan acquisition protocols for SOCT included a radial line scan through the retinochoroiditis lesion, radial line macular scan, and horizontal volume scans at the macula.

Results: The mean age of the five (62.5%) women and three (37.5%) men was 25.7±7.6 years. The mean logMAR ETDRS best-corrected visual acuity was 0.45 (Snellen equivalent, 20/50). SOCT findings of macula were normal in seven patients, and one patient had decreased retinal thickness from a healed chorioretinitis at the fovea. Of eight patients, two had 3+ vitreous haze, four had 2+ vitreous haze, and two had 1+ vitreous haze at presentation. OCT scans revealed vitreous hyperreflective dots in all patients with different densities in different radial scans. Hyperreflective dots were denser in macular scans of eyes in which the active lesion was closer to the fovea.

Conclusions: In this study, visual impairment in majority of the patients was found to be related to vitreous cells and flare. Dense vitritis on macula scans and visual impairment were seen in the patients who had an active lesion closer to the fovea. SOCT may provide objective data of the cellular load of the eyes with posterior segment inflammation.

Author Biographies

Nedime Şahinoğlu Keşkek, Adana Numune Training and Research Hospital, Adana, Turkey
Department of Ophthalmology
Fikret Ünal, Adana Numune Training and Research Hospital, Adana, Turkey
Department of Ophthalmology
Selim Cevher, Adana Numune Training and Research Hospital, Adana, Turkey
Department of Ophthalmology, MD
Şakir Özgür Keşkek, Adana Numune Training and Research Hospital, Adana, Turkey
Department of Internal Medicine
Published
2017-02-28
How to Cite
1.
Şahinoğlu Keşkek N, Ünal F, Cevher S, Keşkek Şakir Özgür (2017) Causes of visual impairment in patients with ocular toxoplasmosis. J Infect Dev Ctries 11:192-195. doi: 10.3855/jidc.7138
Section
Brief Original Articles