Nutritional status is closely related to the severity of COVID-19: a multi-center retrospective study

Yang Li; Chuanwu Zhu; Biao Zhang; Longgen Liu; Fang Ji; Yun Zhao; Juan Cheng; Huaping Shao; Xinying Guan; Fang Ming; Chao Wu; Zhi Xiang Du

doi:10.3855/jidc.14178

Nutritional status is closely related to the severity of COVID-19: a multi-center retrospective study

Authors

Yang Li Department of Infectious Diseases, Taizhou People's Hospital, Taizhou, Jiangsu Province, China
Chuanwu Zhu Department of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, Jiangsu Province, China
Biao Zhang Department of Quality Control Office, Huai'an NO 4 People's Hospital, Huai'an, Jiangsu Province, China
Longgen Liu Department of Infectious Diseases, The Third People's Hospital of Changzhou, Jiangsu Province, China
Fang Ji Department of Infectious Diseases, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China
Yun Zhao Department of Infectious Diseases, The Third People’s Hospital of Yangzhou, Xuzhou, Jiangsu Province, China
Juan Cheng Department of Infectious Diseases, Yancheng Second People’s Hospital, Xuzhou, Jiangsu Province, China
Huaping Shao Department of Infectious Diseases, The People’s Hospital of Suqian, Jiangsu Province, China
Xinying Guan Department of Infectious Diseases, The Affiliated Hospital of Kangda College of Nanjing Medical University,The First People's Hospital of Lianyungang, Jiangsu Province, China
Fang Ming Department of Infectious Diseases, Nantong Third People's Hospital, Nantong University, Jiangsu Province, China
Chao Wu Department of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Jiangsu Province, China
Zhi Xiang Du Department of Infectious Diseases, Taizhou People's Hospital, Taizhou, Jiangsu Province, China

DOI:

https://doi.org/10.3855/jidc.14178

Keywords:

Nutritional status, BMI, ALB, LDH, COVID-19

Abstract

Introduction: Nutritional status has been defined as an individual's health condition. The relationship between the progression of COVID-19 and Nutritional status is still unclear. We analyzed the clinical characteristics of 342 coronavirus disease 2019 (COVID-19) patients, and analyzed the relationship between the progression of COVID-19 and Nutritional status.

Methodology: 342 COVID-19 were enrolled from ten different hospitals in China. The clinical characteristics were collected and analyzed.

Results: The body mass index (BMI) of the mild patients (Group A) was higher than those in severe patients (Group B) and critical patients (Group C); The lactate dehydrogenase (LDH) level of Group A was lower than those of the other two groups; Sex, age, and BMI, was strongly correlated with Clinical classification (CT); Among the laboratory test results, Neutrophil (NEU%), Aspartate aminotransferase (AST), LDH, and blood glucose (BG) were positively correlated with CT; Lymphocyte ( LYM%), Platelet (PLT), Albumin (ALB), and Creatinine (Cr) were negatively correlated with CT. BMI, NEU%, LYM%, ALB, Cr, and PLT are all protective factors that affect CT.

Conclusion: People with poor nutritional status (lower BMI and ALB) have a higher risk of developing severe disease after infection with SARS-CoV-2. In the clinical treatment of COVID-19, individualized nutritional support is very important for the rehabilitation of patients.

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Published

2021-04-30

How to Cite

Li Y, Zhu C, Zhang B, Liu L, Ji F, Zhao Y, Cheng J, Shao H, Guan X, Ming F, Wu C, Du ZX (2021) Nutritional status is closely related to the severity of COVID-19: a multi-center retrospective study. J Infect Dev Ctries 15:490–500. doi: 10.3855/jidc.14178

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Issue

Vol. 15 No. 04: April 2021

Section

Coronavirus Pandemic

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