Unusual presentations of actinomycosis: a case series and literature review

  • Tomislava Skuhala University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
  • Dalibor Vukelić University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
  • Boško Desnica University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
  • Mirjana Balen-Topić University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
  • Andrija Stanimirović Department of Clinical Medicine, University of Applied Health Sciences, Zagreb, Croatia
  • Klaudija Višković University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
Keywords: actinomycosis, skin, stomach, sepsis, penis, treatment

Abstract

Introduction: To review unusual actinomycosis cases that appeared as a diagnostic and therapeutic challenge at our institution and to present a literature review on the usual clinical presentations.

Methodology: This retrospective review included all patients hospitalized for actinomycosis in a 10-year period at the University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia.

Results: A total of 15 patients were hospitalized during the observed period, 9 (60%) females and 6 (40%) males. The localizations of actinomycosis were: pelvis (5), lungs (3), blood stream (2), colon (1), penis (1), stomach (1), skin (1), cervicofacial region (1).

We present four unusual cases: subcutaneous actinomycotic abscess, actinomycosis of the stomach with underlying non-Hodgkin lymphoma, sepsis due to Actinomyces neslundii originated from chronic asymptomatic periapical tooth abscesses and actinomycosis of the distal part of the penile shaft.

Conclusions: Actinomycosis was a very rare clinical problem in our clinical practice (0.032% of all hospitalizations and 0.0034% of all outpatients) but among those cases classical clinical presentations were also very rare.

Published
2021-06-30
How to Cite
1.
Skuhala T, Vukelić D, Desnica B, Balen-Topić M, Stanimirović A, Višković K (2021) Unusual presentations of actinomycosis: a case series and literature review. J Infect Dev Ctries 15:892-896. doi: 10.3855/jidc.13414
Section
Letters to the Editor