The role of 99mTc-ethambutol scintigraphy to diagnose pulmonary tuberculosis

  • Prayudi Santoso Respirology and Critical Illness Division, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0002-7182-386X
  • Basuki Hidayat Department of Nuclear Medicine and Theragnostics Molecular, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia
  • Chica Pratiwi Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0002-3623-0954
  • Kevin Yonatan Budiman Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia
  • Hari Soekersi Department of Radiology, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia
  • Arto Yuwono Soeroto Respirology and Critical Illness Division, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0001-9027-2453
Keywords: Tuberculosis, diagnostic test, 99mTc-ethambutol, scintigraphy

Abstract

Tuberculosis is a significant health problem in many parts of the world. According to the Global Tuberculosis Report 2020, 10 million new tuberculosis cases were reported worldwide in 2019, with only 57% of these cases being bacteriologically confirmed. Current tuberculosis diagnostic tests depend on the quality of the sputum, leaving many diagnostic uncertainties. Diagnostic delays result in ongoing transmission and more severe, progressive disease in the affected person. This shows that current diagnostic tests are not sufficient to establish all tuberculosis cases accurately, and there is a need for a new diagnostic technique. 99mTc-ethambutol scintigraphy was recently reported as a new diagnostic test for tuberculosis, with a sensitivity and specificity of 93.9% and 85.7%, respectively. Here, we report a case of the importance of this new technique for diagnosing tuberculosis when the existing bacteriological and molecular tests failed to confirm the diagnosis.

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Author Biographies

Prayudi Santoso, Respirology and Critical Illness Division, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Division of Respirology and Critical Illness Division, Department of Internal Medicine

Basuki Hidayat, Department of Nuclear Medicine and Theragnostics Molecular, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Department of Nuclear Medicine and Molecular Medicine

Chica Pratiwi, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Department of Internal Medicine

Hari Soekersi, Department of Radiology, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Department of Radiology

Arto Yuwono Soeroto, Respirology and Critical Illness Division, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Division of Respiratory and Critical Illness Medicine

Published
2022-01-31
How to Cite
1.
Santoso P, Hidayat B, Pratiwi C, Budiman KY, Soekersi H, Soeroto AY (2022) The role of 99mTc-ethambutol scintigraphy to diagnose pulmonary tuberculosis. J Infect Dev Ctries 16:226-230. doi: 10.3855/jidc.15148
Section
Case Reports