A study on transmission of Peste des petits ruminants virus between dromedary camels and small ruminants

  • Intisar Kamil Saeed Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Moez Abdulrahman Haj Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Sahar Mohamed Alhassan Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Shaza Mohamed Mutwakil Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Baraa Ahmed Mohammed Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Khalid Mohammed Taha Atbara Veterinary Research Laboratory, River Nile State, Sudan
  • Genevieve Libeau Biological Systems Department - CIRAD Control of Exotic and Emerging Animal Diseases (UMR15) TA A-15/G Campus Int. Baillarguet 34398 Montpellier Cedex 5, France
  • Adama Diallo UMR-ASTRE, Biological Systems Department - CIRAD Conseiller du Directeur de l'ISRA-LNERV ISRA-LNERV BP:2057 Dakar-Hann, Sénégal
  • Yahia Hassan Ali Virology Department, Central Veterinary Research laboratories, Al Amarat, Khartoum, Sudan
  • Abdelmalik Ibrahim Khalafalla Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Shambat, Khartoum North, Sudan
Keywords: PPR, camel, sheep, goat, infection, transmission

Abstract

Introduction: In recent years Peste des petits ruminants (PPR) disease caused several epidemics in a wide range of susceptible hosts. The ability of the peste des petits ruminants virus (PPRV) to cross the species barrier necessitates further research, particularly on disease circulation and cross-species transmission between typical and atypical hosts to guide and facilitate the eradication program anticipated by the Food and Agriculture Organization (FAO) and the World Organization for Animal Health (OIE) in 2030. The aim of this study is to explore the role of dromedary camels as transmitters for PPR.

Methodology: Four experiments were carried out on clinically healthy seronegative camels, sheep and goats. In experiment I, the animals were inoculated with a PPR- positive suspension of camel pneumonic lung homogenate. In the other three experiments either sheep and goats were inoculated and after three days were housed with camels or vice versa.

Results: Marked clinical signs suggestive of PPR were seen in sheep and goats while camels showed mild infection. Severe clinical signs of PPR were seen in sheep and goats when kept with inoculated camels. Postmortem examination revealed PPR lesions in all inoculated animals including camels.

Conclusions: This study showed that dromedary camels infected with PPRV can transmit the disease to sheep and goats, even when they developed mild clinical signs.

Published
2022-02-28
How to Cite
1.
Saeed IK, Haj MA, Alhassan SM, Mutwakil SM, Mohammed BA, Taha KM, Libeau G, Diallo A, Ali YH, Khalafalla AI (2022) A study on transmission of Peste des petits ruminants virus between dromedary camels and small ruminants. J Infect Dev Ctries 16:374-382. doi: 10.3855/jidc.14947
Section
Original Articles