Ferritin / albumin ratio could be a new indicator of COVID-19 disease mortality

Öztürk Taşkin; Ayşe Yilmaz; Veysel Garani Soylu; Ufuk Demir; Funda Çatan Inan

doi:10.3855/jidc.17409

Ferritin / albumin ratio could be a new indicator of COVID-19 disease mortality

Authors

Öztürk Taşkin Kastamonu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Kastamonu, Turkey https://orcid.org/0000-0001-7328-9579
Ayşe Yilmaz Kastamonu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Kastamonu, Turkey https://orcid.org/0000-0001-7635-0830
Veysel Garani Soylu Kastamonu University Faculty of Medicine, Department of Intensive Care, Kastamonu, Turkey https://orcid.org/0000-0002-4617-3367
Ufuk Demir Kastamonu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Kastamonu, Turkey https://orcid.org/0000-0002-0596-8948
Funda Çatan Inan Kastamonu University Faculty of Medicine, Department of Biostatistics, Kastamonu, Turkey

DOI:

https://doi.org/10.3855/jidc.17409

Keywords:

Albumin, COVID-19, ferritin/albumin ratio, ferritin, mortality, predictive

Abstract

Introduction: Despite significant advances in the management of patients with COVID-19, there is a need for markers to guide treatment and predict disease severity. In this study, we aimed to evaluate the relationship of the ferritin/albumin (FAR) ratio with disease mortality.

Methodology: Acute Physiology and Chronic Health Assessment II scores and laboratory results of patients diagnosed with severe COVID-19 pneumonia were retrospectively analyzed. The patients were divided into two groups: survivors and non-survivors. Data for ferritin, albumin, and ferritin/albumin ratio among COVID-19 patients were analyzed and compared.

Results: The mean age was higher in non-survivors (p = 0.778, p < 0.001, respectively). The ferritin/albumin ratio was significantly higher in the non-survival group (p < 0.05). Taking the cut-off value of the ferritin/albumin ratio of 128.71 in the ROC analysis, it predicted the critical clinical status of COVID-19 with 88.4% sensitivity and 88.4% specificity.

Conclusions: ferritin/albumin ratio is a practical, inexpensive, and easily accessible test that can be used routinely. In our study, the ferritin/albumin ratio has been identified as a potential parameter in determining the mortality of critically ill COVID-19 patients treated in intensive care.

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Published

2023-01-31

How to Cite

Taşkin Öztürk, Yilmaz A, Soylu VG, Demir U, Çatan Inan F (2023) Ferritin / albumin ratio could be a new indicator of COVID-19 disease mortality. J Infect Dev Ctries 17:37–42. doi: 10.3855/jidc.17409

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Issue

Vol. 17 No. 01: January 2023

Section

Coronavirus Pandemic

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