A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient

Marija Tomanovic; Vesna Reljic; Jelena Peric; Dubravka Zivanovic

doi:10.3855/jidc.18040

A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient

Authors

Marija Tomanovic Clinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, Serbia https://orcid.org/0000-0002-3068-2319
Vesna Reljic Clinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, Serbia https://orcid.org/0009-0007-5615-5975
Jelena Peric Clinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, Serbia
Dubravka Zivanovic Clinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, Serbia https://orcid.org/0000-0002-9011-3396

DOI:

https://doi.org/10.3855/jidc.18040

Keywords:

Ecthyma gangrenosum, Pseudomonas aeruginosa, sepsis, immunocompromised, Pemphigus vulgaris

Abstract

Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris.

Case presentation: The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.

Conclusions: Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.

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Published

2023-11-30

How to Cite

Tomanovic M, Reljic V, Peric J, Zivanovic D (2023) A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient. J Infect Dev Ctries 17:1654–1657. doi: 10.3855/jidc.18040

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Issue

Vol. 17 No. 11: November 2023

Section

Case Reports

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