Seroprevalence of Hepatitis B Virus Infection and Associated Factors among Cancer Patients at Hawassa University Comprehensive Specialized Hospital, Ethiopia

Surafel Nadew; Zeru Seyoum Wendimagegn; Tinsae Bizuneh; Netsanet Bogale; Sefineh Fenta Feleke; Berihun Mulu Yayeh; Atsede Birhanu Worku; Genanew Mulugeta Kassaw; Mulat Awoke; Amare Nigatu; Natnael Amare Tesfa

doi:10.3855/jidc.18479

Seroprevalence of Hepatitis B Virus Infection and Associated Factors among Cancer Patients at Hawassa University Comprehensive Specialized Hospital, Ethiopia

Authors

Surafel Nadew School of Medicine, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia
Zeru Seyoum Wendimagegn School of Medicine, College of Health Science, Woldia University, Woldia, Ethiopia https://orcid.org/0009-0002-4879-3161
Tinsae Bizuneh School of Medicine, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia
Netsanet Bogale School of Medicine, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia
Sefineh Fenta Feleke School of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia
Berihun Mulu Yayeh School of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia
Atsede Birhanu Worku School of Medicine, College of Health Science, Woldia University, Woldia, Ethiopia
Genanew Mulugeta Kassaw School of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia https://orcid.org/0000-0002-7038-683X
Mulat Awoke School of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia
Amare Nigatu School of Medicine, College of Health Science, Woldia University, Woldia, Ethiopia
Natnael Amare Tesfa School of Medicine, College of Health Science, Woldia University, Woldia, Ethiopia https://orcid.org/0000-0002-9278-1419

DOI:

https://doi.org/10.3855/jidc.18479

Keywords:

Hepatitis B virus, seroprevalence, cancer patients

Abstract

Introduction: Hepatitis B virus infection is a global public health concern and has a high degree of associated morbidity and mortality. In Ethiopia, Hepatitis B virus infection has a variable seroprevalence among different regions with an estimated overall prevalence of around 6%. However, there is a scarcity of data specific to cancer patients.

Methodology: A hospital-based cross-sectional study was conducted among 384 cancer patients who came for follow-up at the oncology unit of Hawassa University Comprehensive Specialized Hospital from January 1/2020 to October 11/2021. A systematic sampling technique was employed to select the participants. Data was collected using structured and interviewer-administered questionnaires and blood samples were drawn from the patients to test hepatitis B virus sero-status. Data was entered to Epi- Data version 4.6 then exported and analysis was done using SPSS version 25. Descriptive statistics were used to describe the study participants. Finally, bivariable and multivariable binary logistic regression was used to identify significantly associated factors.

Results: The seroprevalence of hepatitis B virus infection among cancer patients was 7.6% [95% CI: (4.54 - 9.79)]. Having multiple sexual partners (AOR = 6.24, 95% CI (3.35-16.80)), a history of dental procedures (AOR = 3.34; 95% CI (1.007‑7.66)), and being a hepatocellular carcinoma patient (AOR = 6.13; 95% CI (3.66-18.77)) were factors associated with seropositive status for Hepatitis B virus.

Conclusions: The seroprevalence of Hepatitis B virus infection among cancer patients was high. It is better to consider HBV screening in cancer patients and doing cancer surveillance in HBV-infected patients.

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Published

2024-05-30

How to Cite

Nadew S, Seyoum Wendimagegn Z, Bizuneh T, Bogale N, Fenta Feleke S, Mulu Yayeh B, Birhanu Worku A, Mulugeta Kassaw G, Awoke M, Nigatu A, Tesfa NA (2024) Seroprevalence of Hepatitis B Virus Infection and Associated Factors among Cancer Patients at Hawassa University Comprehensive Specialized Hospital, Ethiopia. J Infect Dev Ctries 18:787–793. doi: 10.3855/jidc.18479

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Issue

Vol. 18 No. 05: May 2024

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Original Articles

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Copyright (c) 2024 Surafel Nadew, Zeru Seyoum Wendimagegn, Tinsae Bizuneh; Netsanet Bogale; Sefineh Fenta Feleke, Berihun Mulu Yayeh, Atsede Birhanu Worku, Genanew Mulugeta Kassaw, Mulat Awoke, Amare Nigatu, Natnael Tesfa

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