Detection of canine parvovirus type 2c (CPV-2c) in Palestine

Ibrahim M Alzuheir; Adnan F Fayyad; Belal Y Abu Helal; Hatem A Atalla; Nasr H Jalboush

doi:10.3855/jidc.18835

Detection of canine parvovirus type 2c (CPV-2c) in Palestine

Authors

Ibrahim M Alzuheir Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, An-Najah National University, P.O. Box 7, Nablus, Palestine https://orcid.org/0000-0002-3280-034X
Adnan F Fayyad Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, An-Najah National University, P.O. Box 7, Nablus, Palestine https://orcid.org/0000-0002-7976-2010
Belal Y Abu Helal Dr. Belal Abu Helal Veterinary Clinic, Tulkarm, P304, Palestine
Hatem A Atalla Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, An-Najah National University, P.O. Box 7, Nablus, Palestine https://orcid.org/0000-0003-4188-7990
Nasr H Jalboush Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, An-Najah National University, P.O. Box 7, Nablus, Palestine https://orcid.org/0000-0002-7180-954X

DOI:

https://doi.org/10.3855/jidc.18835

Keywords:

CPV-2c, dogs, Palestine, phylogenetic analysis, VP2 gene, canine parvovirus

Abstract

Introduction: The objective of the present study was to report, for the first time, the presence of canine parvovirus type 2c (CPV-2c) in domesticated dogs with acute gastroenteritis and to characterize the antigenic variants circulating in Palestine.

Methodology: A veterinary clinical-based epidemiological study was carried out between December 2022 and April 2023. Fifty fecal samples were collected from dogs with gastroenteritis and screened for CPV-2 infection by polymerase chain reaction. The distribution of positive cases according to various epidemiological factors was studied. Partial sequencing of the viral protein 2 (VP2) gene was performed for the analysis of CPV-2 variants.

Results: Most of the investigated samples (60%; n = 50) during the study period were found positive for CPV-2 infection. There was no difference in the distribution of positive cases of CPV-2 infection based on age group, gender, location, and vaccination status. The analysis of nucleotide and amino acid sequences from amplified products, as well as phylogenetic analysis, revealed the presence of CPV-2c clustered with Asian CPV-2c variants.

Conclusions: In summary, this study represents the initial genetic analysis of CPV-2 present in Palestinian dogs with gastroenteritis and provides evidence that confirms the existence of the CPV-2c variants. To determine the prevailing CPV-2 variant associated with the infection, it is crucial to conduct further sequence analysis using large populations of both domestic and wild canines.

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Published

2024-05-30

How to Cite

Alzuheir IM, Fayyad AF, Abu Helal BY, Atalla HA, Jalboush NH (2024) Detection of canine parvovirus type 2c (CPV-2c) in Palestine. J Infect Dev Ctries 18:809–816. doi: 10.3855/jidc.18835

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Issue

Vol. 18 No. 05: May 2024

Section

Original Articles

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