Effects of serial swabs on the nasopharyngeal mucosa: our experience in SARS-CoV2 screening

Authors

  • Giovanni Dell’Aversana Orabona Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy https://orcid.org/0000-0001-6479-6130
  • Vincenzo Abbate Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy
  • Gianluca R De Fazio Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy https://orcid.org/0000-0002-0601-7183
  • Carlo Calvanese Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy
  • Luigi Vaira Maxillofacial Surgery Operative Unit, University Hospital of Sassari, Viale San Pietro 43/B, 07100 Sassari, Italy https://orcid.org/0000-0002-7789-145X
  • Paola Bonavolontà Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy https://orcid.org/0000-0002-3326-4825
  • Antonio Romano Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy https://orcid.org/0000-0003-2932-962X
  • Giovanni Improta Department of Public Health, University of Naples “Federico II”, Naples, Italy https://orcid.org/0000-0002-9485-1687
  • Pasquale Piombino Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy https://orcid.org/0000-0002-8624-0878
  • Luigi Califano Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federic II, Via Pansini 5, 80100 Naples, Italy

DOI:

https://doi.org/10.3855/jidc.17957

Keywords:

COVID-19, SARS CoV-2, nasal swab, swab effect, COVID-19 screening, nasal mucosa

Abstract

Introduction: The purpose of the study was to analyze the effect of swabs on nasal mucosa.

Methodology: Since May 2020, our department was responsible for screening coronavirus disease 2019 (COVID-19) among the employees of a company that continued its activity during the pandemic. The screening protocol consisted of two swabs per week. The samples were analyzed through objective endoscopic and subjective clinical evaluations with sino-nasal outcome test (SNOT Test) at three time points (T0, T1 - three months, T2 - six months).

Results: 23.76% of patients showed an increase in the SNOT score at T1, and the score decreased at T2. This could be due to the phenomenon of "adaptation" of the nasal mucosa. Endoscopic control showed that at T1, secretion, hyperemia, and edema are the most common signs. At T2, however, the crusts accounted for 52.94% of all damage. It is evident that at T1 the endoscopically detected signs of "acute" damage were more represented than at T2, while the signs of "chronic" damage increased as the number of swabs increased.

Conclusions: We demonstrated that mucosal damage and perceived symptoms were absolutely acceptable compared to the diagnostic advantage obtained with serial screening.

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Published

2024-07-29

How to Cite

1.
Dell’Aversana Orabona G, Abbate V, De Fazio GR, Calvanese C, Vaira L, Bonavolontà P, Romano A, Improta G, Piombino P, Califano L (2024) Effects of serial swabs on the nasopharyngeal mucosa: our experience in SARS-CoV2 screening. J Infect Dev Ctries 18:987–992. doi: 10.3855/jidc.17957

Issue

Vol. 18 No. 07: July 2024

Section

Coronavirus Pandemic

License

Copyright (c) 2024 Giovanni Dell' Aversana Orabona, Vincenzo Abbate, Gianluca Renato De Fazio, Carlo Calvanese, Luigi Vaira, Paola Bonavolontà, Antonio Romano, Giovanni Improta, Pasquale Piombino, Luigi Califano

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