Characterization of a CC1153 PVL-producing community-acquired methicillin-resistant Staphylococcus aureus from a dog bite wound

  • Edet Ekpenyong Udo Health Sciences Centre, Kuwait University, Kuwait, Kuwait
  • Samar Saed Boswihi Health Sciences Centre, Kuwait University, Kuwait, Kuwait
  • Tsonyu Ivanov Dimitrov Infectious Disease Hospital, Kuwait, Kuwait
  • Bobby Noronha Health Sciences Centre, Kuwait University, Kuwait, Kuwait
  • Bindu Mathew Health Sciences Centre, Kuwait University, Kuwait, Kuwait
  • Tina Verghese Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Abstract

The isolation of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) strain from an infected dog bite wound is here reported. A 27–year old man presented with a deep open wound on his right hand caused by his dog’s bite at the outpatient clinic of Infectious Disease Hospital (IDH), Kuwait. A wound swab was obtained for bacteriological culture and susceptibility testing. The wound culture yielded pure heavy growth of an MRSA isolate, designated IDH70, which was susceptible to vancomycin, teicoplanin, erythromycin, clindamycin, trimethoprim, fusidic acid and rifampicin. The patient was successfully treated with a combination of rifampicin and cotrimoxazole twice daily for 10 days. Molecular characterization revealed that IDH70 was positive for genes encoding Panton-Valentine leucocidin. IDH70 also carried the SCCmec V genetic element, belonged to coagulase type XIIIa, spa type t903, and was assigned to clonal complex 1153 and sequence type ST1153 (ST1153-V-t903). The report highlights the increasing burden of CA-MRSA in the community and the risk of its acquisition from bites of companion animals.

Author Biographies

Edet Ekpenyong Udo, Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Associate Professor

Department of Microbiology, , Health Sciences Centre

Samar Saed Boswihi, Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Microbiologist, Department of Microbiology, Health Sciences Centre

 

Tsonyu Ivanov Dimitrov, Infectious Disease Hospital, Kuwait, Kuwait

Clinical Microbiologist

Microbiology laboratory, Ministry of Health.

Bobby Noronha, Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Microbiologist, Department of Microbiology, Health Sciences Centre

Bindu Mathew, Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Microbiologist, Department of Microbiology, Health Sciences Centre

Tina Verghese, Health Sciences Centre, Kuwait University, Kuwait, Kuwait

Microbiologist, Department of Microbiology, Health Sciences Centre

Published
2017-06-27
How to Cite
Udo E, Boswihi S, Dimitrov T, Noronha B, Mathew B, Verghese T (2017) Characterization of a CC1153 PVL-producing community-acquired methicillin-resistant Staphylococcus aureus from a dog bite wound. The Journal Of Infection In Developing Countries 11 (06): 513-516. https://doi.org/10.3855/jidc.8954
Section
Case Reports

Keywords

MRSA, MLST, CC1153, PVL