Corynebacterium striatum: an emerging respiratory pathogen

  • Malini Shariff Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India
  • Aditi Aditi Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India
  • Kiran Beri Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India
Keywords: Corynebacterium, diphtheroid, respiratory infection, MDR, RAPD

Abstract

Introduction: Corynebacterium spp. are primarily considered normal flora and dismissed when isolated from clinical specimens. In recent years, Corynebacterium striatum has emerged as a multi-drug resistant human pathogen which can cause nosocomial outbreaks. The organism has infrequently been noted to cause respiratory infections. A retrospective study was conducted to identify the clinical and microbiological features of respiratory infection by Corynebacterium striatum.

Methodology: C. striatum isolates from clinical and surveillance samples were tested for susceptibility to antimicrobials and typed by Random Amplification of Polymorphic DNA (RAPD). Clinical data was obtained through a retrospective review of records.

Results: 15 isolates from clinical and surveillance samples of 11 hospitalised patients were included. The patients suffered from either an exacerbation of COPD (n = 9) or pneumonia (n = 2). The isolates were all multi-drug resistant. RAPD typing found no evidence of an outbreak/ transmission between patients.

Conclusions: Corynebacterium spp. must be considered potential pathogens. Suspicious isolates should be identified to the species level since Corynebacterium striatum is often multi-drug resistant.

Author Biographies

Malini Shariff, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

Professor and Head

Department of Microbiology

 

Aditi Aditi, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

Senior Demonstrator,

Department of Microbiology

Kiran Beri, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

Senior Technical Assistant

Department of Microbiology

Published
2018-07-31
How to Cite
1.
Shariff M, Aditi A, Beri K (2018) Corynebacterium striatum: an emerging respiratory pathogen. J Infect Dev Ctries 12:581-586. doi: 10.3855/jidc.10406
Section
Brief Original Articles