Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya

  • Elfatah Elnifro Department of Medical Microbiology, Medical School, University of Al-Marghib, Al-Kums
  • A.K. Nisha Department of Medical Microbiology, Medical School, University of Al-Marghib, Al-Kums
  • Musbah Almabsoot Department of Microbiology, Postgraduate Academy of Sciences, Tripoli
  • Ali Daeki Department of Medical Microbiology, Faculty of Medicine, Alfatah University for Medical Sciences, Tripoli
  • Nuri Mujber Alkhums Teaching Hospital, Alkhums
  • Jose Muscat Gynecology unit, Saint James Hospital

Abstract

Background: Human parvovirus B19 has been implicated as a primary etiologic agent of erythema infectiosum (fifth disease) and aplastic crisis in patients with chronic haemolytic anemias. Human parvovirus B19 is known to be associated with adverse effects on fetuses such as hydrops fetalis, intrauterine fetal death, and chronic anaemia in immunocompromized individuals. The objective of this study was to assess the seroprevalence of human parvovirus B19 among the pregnant women in Tripoli, Libya.
Methodology: A total number of 150 participants were included in the study, consisting of women of child-bearing age ranging from 18 to 41 years, and divided into age groups as follows: ≤ 21 years, 22-27, 28-32, 33-37, and ≥ 38 years. Specific IgM and IgG antibodies were measured using a commercial ELISA kit.
Results: IgG was observed to be prevalent (61%) among the women of child-bearing age. The sero-prevalence of IgM was found to be 5% overall and there was no detectable IgM in the age group between 33 and 37.
Conclusion: The presence of IgG and absence of IgM indicate immunity to primary infection, but a significant percentage of child-bearing aged women are at risk of primary infection with parvovirus B19 which could adversely affect their pregnancy.
Published
2009-04-01
How to Cite
Elnifro E, Nisha A, Almabsoot M, Daeki A, Mujber N, Muscat J (2009) Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya. The Journal Of Infection In Developing Countries 3 (03): 218-220. https://doi.org/10.3855/jidc.38
Section
Original Articles

Keywords

Medical research