Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya
AbstractBackground: Human parvovirus B19 has been implicated as a primary etiologic agent of erythema infectiosum (fifth disease) and aplastic crisis in patients with chronic haemolytic anemias. Human parvovirus B19 is known to be associated with adverse effects on fetuses such as hydrops fetalis, intrauterine fetal death, and chronic anaemia in immunocompromized individuals. The objective of this study was to assess the seroprevalence of human parvovirus B19 among the pregnant women in Tripoli, Libya.
Methodology: A total number of 150 participants were included in the study, consisting of women of child-bearing age ranging from 18 to 41 years, and divided into age groups as follows: ≤ 21 years, 22-27, 28-32, 33-37, and ≥ 38 years. Specific IgM and IgG antibodies were measured using a commercial ELISA kit.
Results: IgG was observed to be prevalent (61%) among the women of child-bearing age. The sero-prevalence of IgM was found to be 5% overall and there was no detectable IgM in the age group between 33 and 37.
Conclusion: The presence of IgG and absence of IgM indicate immunity to primary infection, but a significant percentage of child-bearing aged women are at risk of primary infection with parvovirus B19 which could adversely affect their pregnancy.
How to Cite
Elnifro E, Nisha A, Almabsoot M, Daeki A, Mujber N, Muscat J (2009) Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya. The Journal Of Infection In Developing Countries 3 (03): 218-220. https://doi.org/10.3855/jidc.38
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).