Positivity rate of respiratory syncytial virus (RSV) using multiplex PCR test in Indonesia

Authors

  • Fariz Nurwidya Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia
  • Ricky Tjahjadi Department of Clinical Pathology, Diagnos Laboratorium, Jakarta 10350, Indonesia https://orcid.org/0000-0002-9077-0230
  • Arini Purwono Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia
  • Linda Mahardhika Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia
  • Fanny Fachrucha Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia

DOI:

https://doi.org/10.3855/jidc.21753

Keywords:

respiratory syncytial virus, RSV, PCR, multiplex PCR, QIAStat-Dx, COVID-19; HRQoL; EQ-5D-5L Indonesia

Abstract

Introduction: Respiratory syncytial virus (RSV) is highly prevalent as a cause of acute respiratory tract infection. Detection of RSV using nucleic acid amplification tests provides rapid results that can help physicians manage patients with acute respiratory symptoms and avoid unnecessary antibiotics. This study aimed to report the positivity rate of RSV among patients with acute respiratory symptoms.

Methodology: Nasopharyngeal swab specimens were obtained from primary healthcare facilities and hospital outpatient clinics from January 2023 to June 2024. The specimens were processed using the multiplex QIAStat-Dx Respiratory SARS-CoV-2 Panel (QIAGEN GmbH, Hilden, Germany).

Results: A total of 1339 tests were performed and RSV was positive in 10.3% of tested patients (138/1339). Regarding the monthly positivity rate, the highest rate of RSV positivity was in November 2023, followed by January 2023, and March 2023.

Conclusions: This study shows a moderate RSV positivity rate in outpatient settings and suggests a seasonal trend, with higher circulation during the rainy season. These findings highlight the value of RSV surveillance for guiding clinical and public health responses in tropical regions.

Author Biographies

Ricky Tjahjadi, Department of Clinical Pathology, Diagnos Laboratorium, Jakarta 10350, Indonesia

Department of Clinical Pathology, Diagnos Laboratorium, Jakarta 10350, Indonesia

Arini Purwono, Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia

Department of Pulmonology and Respiratory Medicine, Universitas Indonesia and Persahabatan Hospital, Jakarta 13230, Indonesia

Fanny Fachrucha, Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine - Persahabatan Hospital, Jakarta 13230, Indonesia

Department of Pulmonology and Respiratory Medicine, Universitas Indonesia and Persahabatan Hospital, Jakarta 13230, Indonesia

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Published

2026-07-31

How to Cite

1.
Nurwidya F, Tjahjadi R, Purwono A, Mahardhika L, Fachrucha F (2026) Positivity rate of respiratory syncytial virus (RSV) using multiplex PCR test in Indonesia. J Infect Dev Ctries 20:926–931. doi: 10.3855/jidc.21753

Issue

Section

Emerging Problems in Infectious Diseases