SPI-7: Salmonella’s Vi-Encoding Pathogenicity Island

  • Helena M. B. Seth-Smith Pathogen Sequencing Unit, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire
Keywords: SPI7, Typhi, typhoid, virulence, PAI, Salmonella

Abstract

Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease. As well as encoding genes which may aid its own transmission, it carries genes for potential virulence factors such as Vi antigen, SopE effector and type IVB pili. The stability of SPI-7 is of interest with respect to typhoid fever and related vaccines.
Published
2008-08-01
How to Cite
1.
Seth-Smith HMB (2008) SPI-7: Salmonella’s Vi-Encoding Pathogenicity Island. J Infect Dev Ctries 2:267-271. doi: 10.3855/jidc.220
Section
Reviews