A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
AbstractBackground: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.
Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.
Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64μg/ml.
Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.
How to Cite
Harish B, Menezes G, Sarangapani K, Parija S (2008) A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India. The Journal Of Infection In Developing Countries 2 (04): 324-327. https://doi.org/10.3855/jidc.229
Enteric fever, Salmonella Typhi, drug resistance
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