Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya

  • Wairimu Chege Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Sherri L Pals Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Eleanor McLellan-Lemal Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Sanjyot Shinde Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Monicah Nyambura Center for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, Kenya
  • Frederick O Otieno Center for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, Kenya
  • Deborah A Gust Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Robert T Chen Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
  • Timothy Thomas Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States

Abstract

Introduction: In an analysis of baseline findings of an HIV incidence cohort study, an assessment was made of HIV prevalence among persons presenting for enrollment and any differences in demographic characteristics between persons not enrolled compared to those enrolled.  We also described and compared HIV risk behaviors in males and females enrolled in the study.

Methodology: A computer-assisted survey was administered to collect baseline demographic and HIV risk data from 1,277 men and women aged 18-34 years. Testing for HIV and other sexually transmitted infections (STI) was conducted.  Out of 1,277 persons prescreened for eligibility, 625 were enrolled.

Results: HIV prevalence of all persons who completed screening was 14.8% (females: 21.1%; males: 8.1%).  The odds of being enrolled in the study were higher for persons 18-24 years compared to those 30-34 years of age [adjusted odds ratio (AOR)=2.18, CI=1.13, 4.21] and males compared to females [AOR=2.07, CI=1.43, 2.99].  Among those enrolled in the study, the most prevalent HIV risk behaviors were unprotected sex (49%), alcohol use (45%), and transactional sex (30%) in the last three months. Compared to females, a significantly greater proportion of males reported using any alcohol or recreational drug in the last three months, a history of oral sex, sex with partner other than a spouse or main partner, ever having a blood transfusion, ever being treated for an STI, and having knowledge of their last HIV test result.

Conclusion: The Kisumu Field Station successfully recruited individuals with HIV risk characteristics for the HIV incidence cohort study.

Author Biographies

Wairimu Chege, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Kenya Medical Research Institute, Medical Officer
Sherri L Pals, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Division of HIV/AIDS Prevention, Statistician
Eleanor McLellan-Lemal, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Division of HIV/AIDS Prevention, Social Scientist
Sanjyot Shinde, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Division of HIV/AIDS Prevention, Data Manager (contractor)
Monicah Nyambura, Center for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, Kenya
Kenya Medical Research Institute, Data Manager
Frederick O Otieno, Center for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, Kenya
Kenya Medical Research Institute, Project Coordinator
Deborah A Gust, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Division of HIV/AIDS Prevention, Behavioral Scientist
Robert T Chen, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Division of HIV/AIDS Prevention, Medical Officer
Timothy Thomas, Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United States
Kenya Medical Research Institute, Medical Officer
Published
2012-12-15
How to Cite
Chege W, Pals S, McLellan-Lemal E, Shinde S, Nyambura M, Otieno F, Gust D, Chen R, Thomas T (2012) Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya. The Journal Of Infection In Developing Countries 6 (12): 870-880. https://doi.org/10.3855/jidc.2636
Section
Original Articles

Keywords

HIV; Kenya; gender differences; risk behaviors