Extra-intestinal salmonellosis in a tertiary care center in South India

  • Sukanya Sudhaharan Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
  • Kanne Padmaja Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
  • Rachana Solanki Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
  • Vemu Lakshmi Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
  • Pamidi Umabala Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
  • Bhaskara Aparna Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
Keywords: Salmonella Typhi, non-typhoidal Salmonella, deep-seated abscesses, endemicity

Abstract

Introduction: The present study is a retrospective analysis of a total of 36 cases of bacteriologically proven extra-intestinal salmonellosis, managed at Nizam’s Institute of Medical Sciences, between 1987 and 2012 (25 years). The extra-intestinal sites involved were the skin, cerebrum, spleen, ovary, synovium, and the skeletal muscle.

Methodology: The extra-intestinal specimens were first processed using standard methods. Colonies suspected as Salmonella were identified by standard laboratory methods, initially by manual biochemical reactions and later by the API system (bioMerieux, Marcy l’Etoile- France) and the Vitek-2 system (bioMerieux). All the Salmonella isolates were sent to Central Research Institute, Kasauli, for serotyping.

Results: The predominant serotype isolated was Salmonella Typhi (S. Typhi) in 27 (75%) patients, followed by Salmonella Senftenberg (S. Senftenberg) in 5 (14%), Salmonella Paratyphi A (S. Paratyphi A) in 3 (8%), and Salmonella Typhimurium (S. Typhimurium) in 1 (3%). There was an increasing resistance to ampicillin, chloramphenicol, cephalosporins (third generation), and quinolones over the 25 years.

Conclusions: The diagnosis of extra-intestinal salmonellosis requires a high degree of clinical suspicion and should be included in the differential diagnosis in patients with deep-seated abscesses.

Author Biographies

Sukanya Sudhaharan, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Specialty Registrar

Department of Microbiology

Nizam's Institute of Medical sciences

Hyderabad

Kanne Padmaja, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Assistant Professor

Department of Microbiology

Rachana Solanki, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Specialty Registrar

Department of Microbiology

Vemu Lakshmi, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Professor & Head

Department of Microbiology

Pamidi Umabala, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Associate Professor

Department of Microbiology

Bhaskara Aparna, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

Technician

Department of Microbiology

Published
2014-07-14
How to Cite
1.
Sudhaharan S, Padmaja K, Solanki R, Lakshmi V, Umabala P, Aparna B (2014) Extra-intestinal salmonellosis in a tertiary care center in South India. J Infect Dev Ctries 8:831-837. doi: 10.3855/jidc.3731
Section
Original Articles