Antimicrobial resistance surveillance of Salmonella isolates from the First People’s Hospital of Yunnan Province, China

  • Jiang Yaxian First People's Hospital of Yunnan Province, China
  • Zuo Hui First People's Hospital of Yunnan Province, China
  • Niu Hua First People's Hospital of Yunnan Province, China
  • Mao Xiaoqin First People's Hospital of Yunnan Province, China
  • Li Fengliang First People's Hospital of Yunnan Province, China
  • Xu Ning First People's Hospital of Yunnan Province, China
  • Li Jiajia First People's Hospital of Yunnan Province, China
  • Jiang Jie First People's Hospital of Yunnan Province, China
  • Zheng Rui First People's Hospital of Yunnan Province, China
Keywords: Salmonella, AntimicrobiSalmonella, antimicrobial drug resistance, ChinaaSalmonella, Chinaal drug resistance, China

Abstract

Introduction: Typhoid fever is a common disease in Yunnan province; however, the resistant phenotype and epidemic characteristics of Salmonella in this area are still unclear. In this study, a 15-year surveillance of antimicrobial susceptibility of Salmonella is reported.

Methodology: From January 1999 to December 2013, Salmonella isolates were recovered from patients in the First People's Hospital of Yunnan Province. Antimicrobial susceptibility was detected and data were analyzed using WHONET5.6.

Results: A total of 845 Salmonella isolates were recovered between 1999 and 2013. The most frequently isolated Salmonella serovar was S. Paratyphi A (93%), and 75.1% (635/845) of the isolates were from the young and middle-aged population. The resistance rates of Salmonella spp. to ciprofloxacin, ampicillin, and ceftriaxone increased dramatically during the 15 years. Carbapenems retained the highest and most stable activity against isolates. The resistance rates of all Salmonella isolates to chloramphenicol and sulfamethoxazole were 0.4% (3/845) and 1.8% (15/845), respectively.

Conclusions: As Salmonella isolates have been observed to be resistant to first-line antibiotics, antimicrobial agents should be used rationally and prescriptions should be based on case-by-case susceptibility testing.

Author Biographies

Jiang Yaxian, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Zuo Hui, First People's Hospital of Yunnan Province, China
Department of Pharmacology
Niu Hua, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Mao Xiaoqin, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Li Fengliang, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Xu Ning, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Li Jiajia, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Jiang Jie, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Zheng Rui, First People's Hospital of Yunnan Province, China
Department of Clinical Laboratory
Published
2015-04-15
How to Cite
1.
Yaxian J, Hui Z, Hua N, Xiaoqin M, Fengliang L, Ning X, Jiajia L, Jie J, Rui Z (2015) Antimicrobial resistance surveillance of Salmonella isolates from the First People’s Hospital of Yunnan Province, China. J Infect Dev Ctries 9:333-337. doi: 10.3855/jidc.5420
Section
Emerging Problems in Infectious Diseases