Pteropine orthoreovirus: An important emerging virus causing infectious disease in the tropics?

  • Yeh Fong Tan International Medical University, Kuala Lumpur, Malaysia
  • Cheong Lieng Teng International Medical University, Kuala Lumpur, Malaysia
  • Kaw Bing Chua Temasek Life Sciences Laboratory, Singapore
  • Kenny Voon International Medical University, Kuala Lumpur, Malaysia
Keywords: Pteropine orthoreovirus, Melaka virus, Nelson Bay virus, Kampar virus, Pulau virus

Abstract

Introduction: Pteropine orthoreovirus (PRV) is an emerging zoonotic respiratory virus that has spilled over from bats to humans. Though initially found only in bats, further case studies have found viable virus in ill patients.

Methodology: PubMed was queried with the keywords of Nelson Bay orthoreovirus OR Pteropine orthoreovirus OR Melaka orthoreovirus OR Kampar orthoreovirus, and returned 17 hits.

Results: Based on prevalence studies, the presence of PRV has been reported in Malaysia and Vietnam, both developing countries. Other case reports also provide further evidence of the presence of PRV in the Southeast Asian region. Despite the absence of PRV in their home countries, travellers from Hong Kong and Japan to Indonesia have returned to their countries ill with this virus, indicating that local communities in Indonesia might be affected by this virus.

Conclusions: This work aims to bring to light this emerging zoonotic respiratory virus circulating among developing countries in Southeast Asia. To improve the understanding of PRV of the medical and scientific community in the Southeast Asian region, this work introduces the general features of PRV, reports of imported PRV, prevalence, and clinical features of PRV. Gaps in knowledge about PRV have also been identified in this work, and we hope that future studies can be undertaken to improve our understanding of this virus.

Author Biographies

Yeh Fong Tan, International Medical University, Kuala Lumpur, Malaysia
Post Graduate Department, Masters Student
Cheong Lieng Teng, International Medical University, Kuala Lumpur, Malaysia
Family Medicine Department, Professor
Kaw Bing Chua, Temasek Life Sciences Laboratory, Singapore
Professor
Kenny Voon, International Medical University, Kuala Lumpur, Malaysia
Post Graduate Department, Senior Lecturer
Published
2017-03-31
How to Cite
1.
Tan YF, Teng CL, Chua KB, Voon K (2017) Pteropine orthoreovirus: An important emerging virus causing infectious disease in the tropics?. J Infect Dev Ctries 11:215-219. doi: 10.3855/jidc.9112
Section
Reviews