Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt

  • Mohamed El Kassas Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Noha Asem Community Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • Amr Abdelazeem Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Ahmad Madkour Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Hamdy Sayed Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Ahmed Tawheed Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Ahmed Al Shafie Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Mahmoud Gamal Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Hassan Elsayed Microbial Biotechnology Department, National Research Centre, Cairo, Egypt
  • Mohamed Badr Critical Care Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
  • Mohamed Hassany Hepatology and Tropical Medicine Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt
  • Dalia Omran Endemic Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • Amr El Fouly Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
Keywords: Egypt, COVID-19, SARS-CoV-2, coronavirus, age group, clinical presentation

Abstract

Introduction: The recently discovered novel coronavirus disease (COVID-19) has emerged in Wuhan, China, since January 2020. Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population.

Methodology: Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data.

Results: Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases.

Conclusions: In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity.

Published
2020-12-31
How to Cite
1.
El Kassas M, Asem N, Abdelazeem A, Madkour A, Sayed H, Tawheed A, Al Shafie A, Gamal M, Elsayed H, Badr M, Hassany M, Omran D, El Fouly A (2020) Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt. J Infect Dev Ctries 14:1352-1360. doi: 10.3855/jidc.13156
Section
Coronavirus Pandemic